Leukotrienes

New Concepts and Targets for Therapy

Inbunden, Engelska, 1998

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Beskrivning

This volume contains the proceedings of the William Harvey Research Conference held in London on the 12th and 13th June 1997. It covers the biosynthesis of leukotrienes, their release in pathological conditions, progress in the characterization of leukotriene receptors, and the elucidation of signal transduction mechanisms following receptor activation. Particular attention has been directed at the use of the increasing number of available leukotriene receptor antagonists and biosynthesis inhibitors in diseases such as asthma and rhinitis.

Produktinformation

Utgivningsdatum:1998-02-28
Mått:155 x 235 x 14 mm
Vikt:404 g
Format:Inbunden
Språk:Engelska
Antal sidor:143
Upplaga:1998
Förlag:Kluwer Academic Publishers
ISBN:9780792387381

Utforska kategorier

Farmakologi inom Medicin

Mer om författaren

Jack Botting is Consultant at the William Harvey Research Institute, an independent charitable foundation within Queen Mary and Westfield College of the University of London, UK.

Innehållsförteckning

1 Molecular mechanisms of leukotriene synthesis: the changing paradigm.- 2 Leukotriene receptors.- 3 Enzymes involved in the production of leukotrienes and related molecules.- 4 Cysteinyl-leukotriene receptors and transduction mechanisms in airway cells.- 5 How to measure leukotrienes in man.- 6 Influence of leukotrienes and anti-leukotrienes on airway tone and migration of inflammatory cells.- 7 Leukotrienes in airways obstruction and inflammation evoked by allergen.- 8 Leukotrienes in induced airway obstruction.- 9 Role of leukotrienes in aspirin-induced asthma.- 10 How to use anti-leukotrienes in the treatment of asthma.- 11 Transcription factors HSF and HF-?B as targets for cytoprotective eicosanoids: a new strategy for therapeutic intervention.- 12 Vascular biology of the leukotrienes.- 13 Leukotrienes in cardiovascular disease.- 14 Leukotriene B4: agonist for the fat regulator PPAR?.- 15 The role of leukotrienes in rhinitis.