Transport Processes in Pharmaceutical Systems

Inbunden, Engelska, 1999

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Beskrivning

This cutting-edge reference clearly explains pharmaceutical transport phenomena, demonstrating applications ranging from drug or nutrient uptake into vesicle or cell suspensions, drug dissolution and absorption across biological membranes, whole body kinetics, and drug release from polymer reservoirs and matrices to heat and mass transport in freeze-drying and hygroscopicity.Focuses on practical applications of drug delivery from a physical and mechanistic perspective, highlighting biological systems.Written by more than 30 international authorities in the field, Transport Processes in Pharmaceutical Systemsdiscusses the crucial relationship between the transport process and thermodynamic factors analyzes the dynamics of diffusion at liquid-liquid, liquid-solid, and liquid-cultured cell interfaces covers prodrug design for improving membrane transport addresses the effects of external stimuli in altering some natural and synthetic polymer matrices examines properties of hydrogels, including synthesis, swelling degree, swelling kinetics, permeability, biocompatibility, and biodegradability presents mass transfer of drugs and pharmacokinetics based on mass balance descriptions and more!Containing over 1000 references and more than 1100 equations, drawings, photographs, micrographs, and tables, Transport Processes in Pharmaceutical Systems is a must-read resource for research pharmacists, pharmaceutical scientists and chemists, chemical engineers, physical chemists, and upper-level undergraduate and graduate students in these disciplines.

Produktinformation

Utgivningsdatum:1999-11-24
Mått:152 x 229 x 44 mm
Vikt:1 540 g
Format:Inbunden
Språk:Engelska
Antal sidor:748
Förlag:Taylor & Francis Inc
ISBN:9780824766108

Utforska kategorier

Tillverkningsteknik inom Naturvetenskap och teknik
Farmakologi inom Medicin
Kemi inom Naturvetenskap och teknik

Mer om författaren

Gordon L. Amidon, Ping I. Lee, Elizabeth M. Topp

Innehållsförteckning

Introduction to Transport ProcessesPrinciples of Mass TransferElizabeth M. ToppAnalytical Solutions to Mass TransferLawrence X. Yu and Gordon L. AmidonPharmacokinetics: Model Structure and Transport SystemsJames M. GalloExperimental Methods to Evaluate Diffusion Coefficients and Investigate Transport Processes of Pharmaceutical InterestJohn W. MaugerDissolution of Pharmaceuticals in Simple and Complex SystemsDaniel P. McNamara, Michael L. Vieira, and John R. CrisonBiological Transport ProcessesBiological Transport Phenomena in the Gastrointestinal Tract: Cellular MechanismsDavid FleisherImproving Oral Drug Transport via ProdrugsMandana AsgharnejadQuantitative Approaches to Delineate Passive Transport Mechanisms in Cell Culture MonolayersNorman F. H. Ho, Thomas J. Raub, Phillip S. Burton, Craig L. Barsuhn, Anthony Adson, Kenneth L. Audus, and Ronald T. BorchardtBarriers to Drug Transport in Ocular EpitheliaUday B. Kompella and Vincent H. L. LeePredicting Oral Drug Absorption in HumansLawrence Yu, Larry Gatlin, and Gordon L. AmidonTransport Processes in Polymer SystemsControlled Release Osmotic Drug Delivery Systems for Oral ApplicationsJohn R. CardinalTransport in Polymer SystemsJim H. KouSynthesis and Properties of Hydrogels Used for Drug DeliveryStevin H. GehrkeStimuli-Modulated Delivery SystemsSung Wan Kim and You Han BaeProperties of Solids that Affect TransportManesh J. Nerurkar, Sarma Duddu, David J. W. Grant, and J. Howard RyttingHeat and Mass TransportHeat and Mass Transfer in Low Pressure Gases: Applications to Freeze DryingMichael J. PikalHeat and Mass Transport: HygroscopicityJames Wright

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