Tachykinin Receptors

AvStephen H. Buck

Inbunden, Engelska, 1994

Del i serien Receptors

1 669 kr

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Beskrivning

This comprehensive review deals with all aspects of Tachykinin receptors in particular, and with neuropeptide/peptide and G-protein linked receptors in general. This book should be of interest to pharmacologists, neuroscientists, biochemists, toxicologists, and molecular and cellular biologists.

Produktinformation

Utgivningsdatum:1994-07-01
Mått:152 x 229 x 40 mm
Vikt:1 088 g
Format:Inbunden
Språk:Engelska
Serie:Receptors
Antal sidor:630
Förlag:Humana Press Inc.
ISBN:9780896032668

Utforska kategorier

Farmakologi inom Medicin
Biovetenskap inom Naturvetenskap och teknik

Recensioner i media

...the major advances in this exciting area of neuropeptide biology are expertly reviewed by many of the leading investigators in this field...a useful volume to both the expert and the uninitiated...the contributors have succeeded in providing the most current information in this field...a well-written and organized text that is a pleasure to read. - Endocrine

Innehållsförteckning

I. Historical Perspectives of Tachykinins.- 1 History of Tachykinin Peptides 1.- 2 History of Tachykinin Receptors 23.- II. Characterization of Tachykinin Receptors.- 3 Biochemical Methods and Assays 39.- 4 Agonist and Antagonist Receptor Binding.- 5 Comparative Distribution of Receptor Types in the Mammalian Brain 101.- 6 Autoradiographic Localization of Receptors in Peripheral Tissues 125.- 7 Molecular Biology of Receptors: Structures, Expression,and Regulatory Mechanisms 165.- 8 Characterization of the NKl Receptor Using Photoaffinity Probes 219.- 9 Modeling of G-Protein-Coupled Receptors: Application to the NK1Tachykinin Receptor 237.- III. Mechanisms of Tachykinin Receptor Action.- 10 Receptors and the Inositol Phosphate—Calcium Signaling System 257.- 11 Signal Transduction Mechanisms of Tachykinin Effects on Ion Channels 285.- IV. Tachykinin Receptor Function.- 12 Structure—Activity Relationships of Agonist and Antagonist Ligands 329.- 13 Pharmacological Characterization of Receptor Types 367.- 14 Evidence for Receptor Subtypes/Species Variants of Receptors. 395.- 15 Role of Receptors in Nociception 471.- 16 Pharmacological Characterization of Receptors in the Spinal Cord of the Newborn Rat 499.- 17•Receptor Function in the Periphery 515.- 18 Receptor Involvement in Pathology and Disease 581.- V. Summary and Future Perspectives.- 19 Summary, Thoughts, and Future Perspectives 611.