Bokus
Marcus Schneck, Janusz Rak, Janusz W. Rak - Oncogene-Directed Therapies, Inbunden

Inbunden, Engelska, 2002

Oncogene-Directed Therapies

Av Marcus Schneck, Janusz Rak, Janusz W. Rak

Del i serien Cancer Drug Discovery and Development

1663 kr

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Beskrivning
Prominent investigators and clinicians summarize in a balanced blend of fundamental science, basic research, experimental therapeutics, and early clinical experiences, what is known about oncogenes and oncogenesis, and describe how that knowledge can be used to treat the cancer. The contributors explain how, why, and under what conditions certain proteins acquire the ability to transform eukaryotic cells, and detail the crucial biological consequences of this oncogenic transformation, particularly for cellular mitogenesis, survival, differentiation, migration, proteolysis, or angiogenic competence. Their articles thoroughly explicate the premises, principles, techniques, and approaches to oncogene targeting in various types of human cancer by using signal transduction inhibitors, immunological targeting methods, and antisense gene therapy.
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Recensioner i media

"The book is well referenced, and readers will easily be able to locate primary literature for in-depth reading on specific topics. The figures and illustrations are extremely useful in summarizing complex topics that are discussed. In summary, this is an unique, well-organized, and timely presentation on a topic of high importance. People who will find this volume especially useful include students of tumor biology, basic scientists with an interest in novel therapeutic or translational research, and all clinicians who are involved in the diagnosis and treatment of patients with cancer." - Neuro-oncology "This book attempts to cover a vast and rapidly evolving field of research, both basic and clinical, and does so successfully by giving the reader a balanced mix of basic science, experimental therapeutics and clinical observations. Most chapters are richly illustrated and all have extensive lists of relevant references." - Medical Oncology "...this book will be useful not only to those just starting their research careers, including graduate and medical students, but also to those who have been involved in the field of cancer biology and treatment for a number of years, including seasoned scientists and clinicians." -Doody's Health Sciences Book Review Journal

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