Introduction to Cancer Biology

Robin Hesketh is Emeritus Professor in the Department of Biochemistry, University of Cambridge. He is also a Fellow of Selwyn College. His major research area is anti-angiogenic strategies for cancer therapy. He has lectured in undergraduate and post-graduate courses on cell and molecular biology and cancer and published over 100 research papers and seven books, including the 1st edition of Introduction to Cancer Biology (2012) and Understanding Cancer (2022) for Cambridge University Press.

'A comprehensive, engagingly written, accurate overview of a topic that has continued to rapidly evolve in recent years. As our knowledge of cancer's molecular underpinnings advances, it is essential to remain up-to-date and this book delivers. Each chapter is full of concise explanations and wonderful illustrations that convey complex concepts in a straightforward way. I highly recommend this valuable resource to all students of biology and medicine.' Andrew Lam, M.D., University of Massachusetts Medical School

• Preface; 1. Lessons from epidemiology; 2. Causes of cancer; 3. Genetic analysis of cancer; 4. Signaling in normal cells; 5. 'Cancer genes': Mutations and cancer development; 6. What is a tumour? 7. Cancer signaling networks; 8. Cancer detection, diagnosis and radiotherapy; 9. Cancer chemotherapy; 10. The future of cancer detection and treatment; Appendix A: Tumour grading and staging; Appendix B: Classes of major oncoproteins; Appendix C: Major tumour suppressor genes; Appendix D: Ten major cancers at a glance; Glossary, References, Index.