Kate McCombe, Consultant Anaesthetist, Frimley Health NHS Trust, Surrey, UKLara Wijayasiri, Consultant Anaesthetist, Ashford and St Peter’s Hospitals NHS Trust, Surrey, UK

• Part 1 - Pharmacology1 Receptors2 Mechanism of Drug Action3 Drug Interactions4 Drug Absorption and Bioavailability5 Drugs and the Liver6 Drugs and the Kidney7 Variations in Drug Metabolism8 Isomers9 Drugs to Draw10 Exponential Functions11 Dose–Response Curves12 First- and Zero-Order Kinetics13 Volume of Distribution, Clearance and Half-Life14 Compartment Models15 Total Intravenous Anaesthesia16 Induction Agents17 Nitrous Oxide18 Inhalational Anaesthetic Agents (Volatile Agents)19 Neuromuscular Blocking Drugs20 Cholinesterase Inhibitors (Anticholinesterases) And Reversal Agents21 Antimuscarinic Drugs22 Opioids23 Sedative Agents24 Local Anaesthetics25 Antiemetics and Prokinetics26 Antiarrhythmic Drugs27 Antihypertensive Agents28 Diuretics29 Non-Steroidal Anti-Inflammatory Drugs30 Antimicrobials31 Anticoagulants32 Anti-Platelet Agents33 Blood34 Hypoglycaemic Agents35 Anticonvulsants36 Antidepressants37 Drugs used to Treat Asthma38 Miscellaneous DrugsPart 2 - Special patient groups39 The Jehovah’s Witness40 Obesity41 Paediatric Patient42 Pregnancy43 Pre-Eclampsia Toxaemia44 Elderly Patient45 Down’s Syndrome46 Sickle Cell Anaemia47 Rheumatoid Arthritis48 Diabetes49 Hypertensive Patient50 Chronic Obstructive Pulmonary Disease51 Burns and Trauma52 Brainstem Death and Organ DonationPart 3 - Critical incidents53 Anaphylaxis54 Aspiration55 Awareness56 Blood Transfusion Error57 Bradycardia58 Cyanosis59 Difficult to Ventilate (High Airway Pressures)60 Failed Intubation61 Failure to Breathe62 High Spinal Block63 Hypertension64 Hypotension65 Hypoxia66 Intra-Arterial Injection67 Laryngospasm68 Local Anaesthetic Toxicity69 Major Obstetric Haemorrhage70 Malignant Hyperpyrexia71 Needlestick Injury72 Post-Dural Puncture Headache73 ST Segment Changes74 Tachyarrhythmias75 Venous Air Embolism (VAE)

Kate McCombe, Consultant Anaesthetist, Frimley Health NHS Trust, Surrey, UKLara Wijayasiri, Consultant Anaesthetist, Ashford and St Peter’s Hospitals NHS Trust, Surrey, UK

• Part 1 - Pharmacology1 Receptors2 Mechanism of Drug Action3 Drug Interactions4 Drug Absorption and Bioavailability5 Drugs and the Liver6 Drugs and the Kidney7 Variations in Drug Metabolism8 Isomers9 Drugs to Draw10 Exponential Functions11 Dose–Response Curves12 First- and Zero-Order Kinetics13 Volume of Distribution, Clearance and Half-Life14 Compartment Models15 Total Intravenous Anaesthesia16 Induction Agents17 Nitrous Oxide18 Inhalational Anaesthetic Agents (Volatile Agents)19 Neuromuscular Blocking Drugs20 Cholinesterase Inhibitors (Anticholinesterases) And Reversal Agents21 Antimuscarinic Drugs22 Opioids23 Sedative Agents24 Local Anaesthetics25 Antiemetics and Prokinetics26 Antiarrhythmic Drugs27 Antihypertensive Agents28 Diuretics29 Non-Steroidal Anti-Inflammatory Drugs30 Antimicrobials31 Anticoagulants32 Anti-Platelet Agents33 Blood34 Hypoglycaemic Agents35 Anticonvulsants36 Antidepressants37 Drugs used to Treat Asthma38 Miscellaneous DrugsPart 2 - Special patient groups39 The Jehovah’s Witness40 Obesity41 Paediatric Patient42 Pregnancy43 Pre-Eclampsia Toxaemia44 Elderly Patient45 Down’s Syndrome46 Sickle Cell Anaemia47 Rheumatoid Arthritis48 Diabetes49 Hypertensive Patient50 Chronic Obstructive Pulmonary Disease51 Burns and Trauma52 Brainstem Death and Organ DonationPart 3 - Critical incidents53 Anaphylaxis54 Aspiration55 Awareness56 Blood Transfusion Error57 Bradycardia58 Cyanosis59 Difficult to Ventilate (High Airway Pressures)60 Failed Intubation61 Failure to Breathe62 High Spinal Block63 Hypertension64 Hypotension65 Hypoxia66 Intra-Arterial Injection67 Laryngospasm68 Local Anaesthetic Toxicity69 Major Obstetric Haemorrhage70 Malignant Hyperpyrexia71 Needlestick Injury72 Post-Dural Puncture Headache73 ST Segment Changes74 Tachyarrhythmias75 Venous Air Embolism (VAE)