Heterogeneous Catalysis

A Versatile Tool for the Synthesis of Bioactive Heterocycles

AvK.L. Ameta Ph.D.,Andrea Penoni

Häftad, Engelska, 2021

789 kr

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For more than a century, bioactive heterocycles have formed one of the largest areas of research in organic chemistry. They are important from a biological and industrial point of view as well as to the understanding of life processes and efforts to improve the quality of life. Heterogeneous Catalysis: A Versatile Tool for the Synthesis of Bioactive Heterocycles highlights the recent methodologies used in the synthesis of such bioactive systems and focuses on the role of heterogeneous catalysis in the design and synthesis of various biologically active heterocyclic compounds of pharmacological interest. Topics include:Synthetic protocols for the construction of heterocyclic systems employing silica-bound catalystsRecent advances in heterogeneous copper-catalyzed reactions for the synthesis of bioactive heterocyclesFeatures of silica-based heterogeneous catalysts, such as abundance, ease of use, and stabilityUltrasound as an effective tool for accelerating reactionsOrganic transformations catalyzed by nano-ZnO as a valuable heterogeneous catalystHeterogeneous catalysts employed in the synthesis of coumarinsHeterocyclizations in the presence of silver salts Home-made organometallic silica sources, known as silatranes Reflecting the focused studies currently conducted in these areas, the book also examines anticancer, antifungal, antibacterial, anti-HIV, anti-inflammatory, antioxidant, and many more biological activities of heterocyclic compounds. It is essential reading for postgraduate and research scholars in the fields of biochemistry, chemical biology, medicinal chemistry and pharmaceutical chemistry.

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