Encyclopedia of Drug Metabolism and Interactions, Clinical Aspects

The ideal place to begin researching any question involving drug metabolism and interactionsThe Encyclopedia of Drug Metabolism and Interactions provides essential support during all phases of drug development, from drug design to drug action and interaction within the human body. This six-volume work covers both preclinical and clinical aspects of drug metabolism and interactions. It also provides a wealth of toxicological, regulatory, and marketing information, all written and edited by leading international experts in the field.By collecting and reviewing the current literature in the field in one expertly organized work, this encyclopedia is the ideal place to begin researching any question involving drug metabolism and interactions. Readers will find such important topics and working tools as: Inhibited or induced enzymes and their impact on drug toxicity and altered response in both animal and human modelsEffects of both genetic and non-genetic factors on drug metabolismRelationships between a drug metabolism, its activation or inactivation, and a drug's potential toxicity/safetyExamples demonstrating all aspects of drug metabolism and interactions in silico, in vitro, in laboratory animals, and in humansMethods and protocols enabling readers to perform seamless studies of metabolism and drug interactionsAll articles are based on recent findings and standards of practice. By reviewing and contextualizing the current literature, the authors offer new perspectives on our current state of knowledge as well as future directions for research in drug metabolism and interactions. References at the end of each article serve as a gateway to the literature.The Encyclopedia of Drug Metabolism and Interactions is recommended for researchers, physicians, and students at all levels. It introduces the basics to novices and explores the latest science and applications for more experienced investigators.