Charles O. Thoen, DVM, PhD, is Professor and former Chairman of the Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University. He is former Chairman of the IUATLD Scientific Committee on Tuberculosis in Animals; former Chairman of the WHO Committee on Animal Tuberculosis; Former Head of the Mycobacteria and Brucella Section, National Veterinary Services Laboratories, Veterinary Services, Animal and Plant Health Inspection Service, USDA; and former Research Fellow in Microbiology, Mayo Graduate School of Medicine, University of Minnesota.James H. Steele, DVM, MPH, was previously Professor Emeritus, Environmental Health, The University of Texas$en$Houston School of Public Health, Center for Infectious Diseases, Houston, TX. Dr. Steele was formerly Chief Veterinary Officer, Assistant Surgeon General, U.S. Public Health Service, and Consult to United Nations agencies, WHO, Food and Agriculture Organization, PAHO, International Atomic Energy Organization, and the World Bank.John B. Kaneene, DVM, MPH, PhD, FAES, FAVES, is a University Distinguished Professor of Epidemiology and Public Health. He is the founding and current Director of the Center for Comparative Epidemiology at Michigan State University. Dr. Kaneene is a current member of the IUATLD and is a former Program Secretary and Chairperson of the zoonotic tuberculosis subcommittee of the IUATLD. Dr. Kaneene has active research on the molecular and quantitative epidemiology of zoonotic TB in several countries in Asia and Africa.

“The third edition complements the previous editions and will be a useful text for readers interested in both human and animal tuberculosis.”  (Journal of the American Veterinary Medical Association, 15 September 2014)“Zoonotic Tuberculosis’ is a superb text and should be placed on the shelf alongside the previous editions for anyone wanting to know more about the global management of tuberculosis.”  (Veterinary Record, 21 June 2014)

• Contributors ixPreface xv1 Tuberculosis in animals and humans: An introduction 3Charles O. Thoen, Philip A. LoBue, and Donald A. Enarson2 One Health approach for preventing and controlling tuberculosis in animals and humans 9John B. Kaneene, Bruce Kaplan, James H. Steele, and Charles O. Thoen3 Public health significance of zoonotic tuberculosis caused by the Mycobacterium tuberculosis complex 21Adam J. Langer and Philip A. LoBue4 Mycobacterium bovis infection in humans and animals with an emphasis on countries in Central and South America 35Isabel N. de Kantor, Pedro M. Torres, Eliana Roxo, Alfredo Garin, Luis A. Paredes Noack, María D. Sequeira, María Susana Imaz, Nora Morcillo, and María Alice da Silva Telles5 Pathogenesis of tuberculosis caused by Mycobacterium bovis 51Charles O. Thoen and Raúl G. Barletta6 Epidemiology of Mycobacterium bovis 63Julian A. Drewe, Dirk U. Pfeiffer, and John B. Kaneene7 Molecular epidemiology of Mycobacterium bovis 79Julian A. Drewe and Noel H. Smith8 New and current approaches for isolation, identification, and genotyping of Mycobacterium bovis 89Suelee Robbe-Austerman and Claude Turcotte9 Tuberculosis in animals in South Africa 99Nick Kriek10 Status and control of bovine tuberculosis in Ethiopia 109Asseged Bogale, Berhanu Tameru, and Tsegaye Habtemariam11 Distribution, public health significance, and control status of bovine tuberculosis caused by Mycobacterium bovis in Uganda 133David Nganwa and Asseged Bogale12 Bovine tuberculosis: Epidemiology, zoonotic transmission, activities, and challenges toward its control in Nigeria 149Simeon I.B. Cadmus and F. Olalekan Ayanwale13 Factors contributing to the transmission of bovine tuberculosis caused by Mycobacterium bovis and its control status in Sudan 159Ehsan Abdalla and David Nganwa14 Overview of bovine tuberculosis in Ghana 175Gregory Banayah Mwinyelle and Andy Alhassan15 Status and control of tuberculosis in animals in Pakistan 181M. Tariq Javed16 Zoonotic tuberculosis in humans, elephants, and other animals in Nepal 191Mahesh Bhandari and Charles O. Thoen17 Zoonotic tuberculosis in India 197Rishendra Verma18 An overview of Mycobacterium bovis infections in domestic and wild animals in Korea 203Han Sang Yoo and Kyoungjin J. Yoon19 Mycobacterium bovis infection and control in China 213Aizhen Guo, Yingyu Chen, and Huanchun Chen20 Zoonotic tuberculosis in Australia and New Zealand 221Graham Nugent and Debra V. Cousins21 Bovine tuberculosis eradication in the United States: A century of progress 235Alecia Larew Naugle, Mark Schoenbaum, C. William Hench, Owen L. Henderson, and Jack Shere22 The occurrence of M. bovis cases in U.S. cattle, 2001–2011 253Katie Portacci, Jason Lombard, Mark Schoenbaum, Kathleen Orloski, and Mark Camacho23 The importance of M. bovis infection in cervids on the eradication of bovine tuberculosis in the United States 263Michael J. Gilsdorf and John B. Kaneene24 Evaluation of antemortem diagnostic tests for detecting bovine tuberculosis infection in the United States 277Mark Schoenbaum, María Celia Antognoli, and Kathleen Orloski25 Canada’s bovine tuberculosis eradication program: Past and present 287Noel Harrington, Krista Howden, and Claude Turcotte26 Bovine tuberculosis eradication program in Mexico 291Alejandro Perera Ortiz, José Alfredo Gutiérrez-Reyes, Estela Flores Velázquez, Guillermo Agustín Reyes Escalona, and Eli Tonatiuh Selva Hernández27 Epidemiology of bovine tuberculosis in the Republic of Serbia with a brief overview of the current epidemiological situation in the region 309Dejan Krnjaic, Budimir Plavsic, and Slavoljub Stanojevic28 The impact of an integrated wildlife and bovine tuberculosis eradication program in Ireland 323Michael Sheridan, Margaret Good, Simon J. More, and Eamonn Gormley29 Bovine tuberculosis eradication in France 341María Laura Boschiroli and Jean-Jacques Bénet30 Animal tuberculosis in Spain: A multihost system 349Christian Gortazar and Mariana Boadella31 Tuberculosis eradication in Italy 357Laura Chiavacci, Alessandro Dondo, Maria Goria, Giuliana Moda, Luigi Ruocco, Patrizia Vignetta, and Simona Zoppi32 Status of bovine tuberculosis control in countries of Central Europe and countries of the former Soviet Union 369Ivo Pavlik 33 Zoonotic tuberculosis in nonhuman primates 383Pat A. Frost, Paul P. Calle, Hilton Klein, and Charles O. ThoenIndex 399

Charles O. Thoen, DVM, PhD, is Professor and former Chairman of the Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University. He is former Chairman of the IUATLD Scientific Committee on Tuberculosis in Animals; former Chairman of the WHO Committee on Animal Tuberculosis; Former Head of the Mycobacteria and Brucella Section, National Veterinary Services Laboratories, Veterinary Services, Animal and Plant Health Inspection Service, USDA; and former Research Fellow in Microbiology, Mayo Graduate School of Medicine, University of Minnesota.James H. Steele, DVM, MPH, was previously Professor Emeritus, Environmental Health, The University of Texas$en$Houston School of Public Health, Center for Infectious Diseases, Houston, TX. Dr. Steele was formerly Chief Veterinary Officer, Assistant Surgeon General, U.S. Public Health Service, and Consult to United Nations agencies, WHO, Food and Agriculture Organization, PAHO, International Atomic Energy Organization, and the World Bank.John B. Kaneene, DVM, MPH, PhD, FAES, FAVES, is a University Distinguished Professor of Epidemiology and Public Health. He is the founding and current Director of the Center for Comparative Epidemiology at Michigan State University. Dr. Kaneene is a current member of the IUATLD and is a former Program Secretary and Chairperson of the zoonotic tuberculosis subcommittee of the IUATLD. Dr. Kaneene has active research on the molecular and quantitative epidemiology of zoonotic TB in several countries in Asia and Africa.

“The third edition complements the previous editions and will be a useful text for readers interested in both human and animal tuberculosis.”  (Journal of the American Veterinary Medical Association, 15 September 2014)“Zoonotic Tuberculosis’ is a superb text and should be placed on the shelf alongside the previous editions for anyone wanting to know more about the global management of tuberculosis.”  (Veterinary Record, 21 June 2014)

• Contributors ixPreface xv1 Tuberculosis in animals and humans: An introduction 3Charles O. Thoen, Philip A. LoBue, and Donald A. Enarson2 One Health approach for preventing and controlling tuberculosis in animals and humans 9John B. Kaneene, Bruce Kaplan, James H. Steele, and Charles O. Thoen3 Public health significance of zoonotic tuberculosis caused by the Mycobacterium tuberculosis complex 21Adam J. Langer and Philip A. LoBue4 Mycobacterium bovis infection in humans and animals with an emphasis on countries in Central and South America 35Isabel N. de Kantor, Pedro M. Torres, Eliana Roxo, Alfredo Garin, Luis A. Paredes Noack, María D. Sequeira, María Susana Imaz, Nora Morcillo, and María Alice da Silva Telles5 Pathogenesis of tuberculosis caused by Mycobacterium bovis 51Charles O. Thoen and Raúl G. Barletta6 Epidemiology of Mycobacterium bovis 63Julian A. Drewe, Dirk U. Pfeiffer, and John B. Kaneene7 Molecular epidemiology of Mycobacterium bovis 79Julian A. Drewe and Noel H. Smith8 New and current approaches for isolation, identification, and genotyping of Mycobacterium bovis 89Suelee Robbe-Austerman and Claude Turcotte9 Tuberculosis in animals in South Africa 99Nick Kriek10 Status and control of bovine tuberculosis in Ethiopia 109Asseged Bogale, Berhanu Tameru, and Tsegaye Habtemariam11 Distribution, public health significance, and control status of bovine tuberculosis caused by Mycobacterium bovis in Uganda 133David Nganwa and Asseged Bogale12 Bovine tuberculosis: Epidemiology, zoonotic transmission, activities, and challenges toward its control in Nigeria 149Simeon I.B. Cadmus and F. Olalekan Ayanwale13 Factors contributing to the transmission of bovine tuberculosis caused by Mycobacterium bovis and its control status in Sudan 159Ehsan Abdalla and David Nganwa14 Overview of bovine tuberculosis in Ghana 175Gregory Banayah Mwinyelle and Andy Alhassan15 Status and control of tuberculosis in animals in Pakistan 181M. Tariq Javed16 Zoonotic tuberculosis in humans, elephants, and other animals in Nepal 191Mahesh Bhandari and Charles O. Thoen17 Zoonotic tuberculosis in India 197Rishendra Verma18 An overview of Mycobacterium bovis infections in domestic and wild animals in Korea 203Han Sang Yoo and Kyoungjin J. Yoon19 Mycobacterium bovis infection and control in China 213Aizhen Guo, Yingyu Chen, and Huanchun Chen20 Zoonotic tuberculosis in Australia and New Zealand 221Graham Nugent and Debra V. Cousins21 Bovine tuberculosis eradication in the United States: A century of progress 235Alecia Larew Naugle, Mark Schoenbaum, C. William Hench, Owen L. Henderson, and Jack Shere22 The occurrence of M. bovis cases in U.S. cattle, 2001–2011 253Katie Portacci, Jason Lombard, Mark Schoenbaum, Kathleen Orloski, and Mark Camacho23 The importance of M. bovis infection in cervids on the eradication of bovine tuberculosis in the United States 263Michael J. Gilsdorf and John B. Kaneene24 Evaluation of antemortem diagnostic tests for detecting bovine tuberculosis infection in the United States 277Mark Schoenbaum, María Celia Antognoli, and Kathleen Orloski25 Canada’s bovine tuberculosis eradication program: Past and present 287Noel Harrington, Krista Howden, and Claude Turcotte26 Bovine tuberculosis eradication program in Mexico 291Alejandro Perera Ortiz, José Alfredo Gutiérrez-Reyes, Estela Flores Velázquez, Guillermo Agustín Reyes Escalona, and Eli Tonatiuh Selva Hernández27 Epidemiology of bovine tuberculosis in the Republic of Serbia with a brief overview of the current epidemiological situation in the region 309Dejan Krnjaic, Budimir Plavsic, and Slavoljub Stanojevic28 The impact of an integrated wildlife and bovine tuberculosis eradication program in Ireland 323Michael Sheridan, Margaret Good, Simon J. More, and Eamonn Gormley29 Bovine tuberculosis eradication in France 341María Laura Boschiroli and Jean-Jacques Bénet30 Animal tuberculosis in Spain: A multihost system 349Christian Gortazar and Mariana Boadella31 Tuberculosis eradication in Italy 357Laura Chiavacci, Alessandro Dondo, Maria Goria, Giuliana Moda, Luigi Ruocco, Patrizia Vignetta, and Simona Zoppi32 Status of bovine tuberculosis control in countries of Central Europe and countries of the former Soviet Union 369Ivo Pavlik 33 Zoonotic tuberculosis in nonhuman primates 383Pat A. Frost, Paul P. Calle, Hilton Klein, and Charles O. ThoenIndex 399