Fundamentals of Industrial Chemistry

John Tyrell teaches a number of chemistry courses that include Industrial and Polymer Chemistry in the Department of Chemistry and Biochemistry at the University of North Carolina Wilmington. Dr. Tyrell holds sixty-eight patents and has more than twenty years of industrial research experience, at Lederle Laboratories, General Electric Plastics, and OxyChem. He co-authored the book Fundamentals of Heterocyclic Chemistry: Importance in Nature and in the Synthesis of Pharmaceuticals which was published by Wiley.

“Useful for students in chemistry or chemical engineering as well as entry-level industrial employees.”  (Choice, 1 February 2015)

• 1. Introduction 1References 32. Inorganic Chemicals 52.1 Sulfuric acid 52.2 Phosphoric acid 72.3 Lime 92.4 Soda Ash 102.5 Titanium Dioxide 102.6 Sodium Chloride and Chloralkali 11Questions 14References 153. Gases 173.1 Syn Gas 173.2 Nitrogen and Oxygen 243.3 Ammonia 26Questions 31References 324. Patents 35Questions 43References 465. Petrochemicals 475.1 Crude Oil 475.2 Coal, Natural Gas and Shale Oil 525.3 Ethylene 535.4 Propylene 575.5 BTX 59 Questions 60References 616. Business Considerations 636.1 Introduction 636.2 Six Sigma 646.3 Stage-Gate™ 666.4 Organization 686.5 Gantt Charts 706.6 Cost Estimates 716.7 Scale-up Considerations 75Questions 82References 837. Polymer Basics 85Questions 104References 1068. Some Industrially Important Polymers 1098.1 Polyethylene 1098.2 Polypropylene 1128.3 Polyvinyl Chloride 1138.4 Other Olefin Polymers 1168.5 Polyester 1178.6 Polycarbonate 1218.7 Nylon 1228.8 Polyimide 1258.9 Fluoropolymers 1268.10 Polyphenylene Sulfide 1288.11 Acetal Resin 1298.12 Thermosets 130Questions 136References 1399. Blends and Additives 1419.1 Blends 1419.2 Antioxidants 1439.3 UV Stabilizers 1479.4 Antistatic Agents 1489.5 Peroxides 1499.6 Lubricants 1519.7 Flame Retardants 1519.8 Heat Stabilizers 1559.9 Plasticizers 1569.10 Others 157Questions 159References 16110. Pharmaceuticals 16310.1 The Drug Development Process 16310.2 Regulation 16510.3 Synthetic Considerations 16910.4 Chirality 172Questions 179References 18111. Pharmaceuticals–Some Important Drugs 18311.1 Introduction 18311.2 Cholesterol Drugs 18411.3 Hypertension 18711.4 Proton Pump Inhibitors 19311.5 Diabetes 19511.6 Antidepressants 198References 20112. Agricultural Chemicals 20312.1 Overview 20312.2 Fertilizer 20412.3 Insecticides 20512.4 Herbicides 21112.5 Fungicides 217References 21913. Design of Experiments and Statistical Process Control 22313.1 Introduction 22313.2 Design of Experiments 22913.3 Statistical Process Control 232Questions 237Reference 23714. Safety and Environmental Considerations 23914.1 Safety and Responsible Care 23914.2 Environmental Compliance 24314.3 Green Chemistry 245Questions 249References 250Index 251