Malcolm D. C. Donaldson, MD, FRCP, FRCPCH, DCH, Honorary Senior Research Fellow, Glasgow University School of Medicine, Honorary Consultant Paediatrician, Royal Hospital for Children, Glasgow, UK. John W. Gregory, MBChB, MD, FRCP, DCH, FRCPCH, Professor in Paediatric Endocrinology & Honorary Consultant, Division of Population Medicine, School of Medicine, Cardiff University, Heath Park, Cardiff, UK. Guy Van Vliet, MD, Staff Endocrinologist, CHU Sainte-Justine and Professor of Pediatrics, University of Montreal, Montreal, QC, Canada. Joseph I. Wolfsdorf, MB, BCh, MA, DCH, FCP, FAAP, Attending Physician in Endocrinology, Boston Children's Hospital Chair in Endocrinology, Professor of Pediatrics, Harvard Medical School, Boston, Massachusetts, U.S.A.

• Preface to the Fourth Edition ixAcknowledgements xiAbbreviations xiii1 Diabetes Mellitus 12 Hypoglycaemia 573 Short Stature 714 Tall Stature 1055 Puberty 1156 Thyroid Disorders 1437 Differences in Sex Development and Common Genital Anomalies 1698 Adrenal Disorders 1819 Salt and Water Balance 20310 Calcium and Bone 21711 Obesity 23512 Endocrine Effects of Cancer Treatment 247Supplementary chapter by Johnny Deladoëy13 An Endocrinologist’s Guide to Genetics in the Age of Genomics 257Appendix 1 Growth Charts and Body Mass Index (BMI) Charts 271Appendix 2 Syndrome-specific Growth Charts 287Appendix 3 Congenital Adrenal Hyperplasia (CAH) Therapy Card 299Index 301

Malcolm D. C. Donaldson, MD, FRCP, FRCPCH, DCH, Honorary Senior Research Fellow, Glasgow University School of Medicine, Honorary Consultant Paediatrician, Royal Hospital for Children, Glasgow, UK. John W. Gregory, MBChB, MD, FRCP, DCH, FRCPCH, Professor in Paediatric Endocrinology & Honorary Consultant, Division of Population Medicine, School of Medicine, Cardiff University, Heath Park, Cardiff, UK. Guy Van Vliet, MD, Staff Endocrinologist, CHU Sainte-Justine and Professor of Pediatrics, University of Montreal, Montreal, QC, Canada. Joseph I. Wolfsdorf, MB, BCh, MA, DCH, FCP, FAAP, Attending Physician in Endocrinology, Boston Children's Hospital Chair in Endocrinology, Professor of Pediatrics, Harvard Medical School, Boston, Massachusetts, U.S.A.

• Preface to the Fourth Edition ixAcknowledgements xiAbbreviations xiii1 Diabetes Mellitus 12 Hypoglycaemia 573 Short Stature 714 Tall Stature 1055 Puberty 1156 Thyroid Disorders 1437 Differences in Sex Development and Common Genital Anomalies 1698 Adrenal Disorders 1819 Salt and Water Balance 20310 Calcium and Bone 21711 Obesity 23512 Endocrine Effects of Cancer Treatment 247Supplementary chapter by Johnny Deladoëy13 An Endocrinologist’s Guide to Genetics in the Age of Genomics 257Appendix 1 Growth Charts and Body Mass Index (BMI) Charts 271Appendix 2 Syndrome-specific Growth Charts 287Appendix 3 Congenital Adrenal Hyperplasia (CAH) Therapy Card 299Index 301

Malcolm D. C. Donaldson, MD, FRCP, FRCPCH, DCH, Honorary Senior Research Fellow, Glasgow University School of Medicine, Honorary Consultant Paediatrician, Royal Hospital for Children, Glasgow, UK. John W. Gregory, MBChB, MD, FRCP, DCH, FRCPCH, Professor in Paediatric Endocrinology & Honorary Consultant, Division of Population Medicine, School of Medicine, Cardiff University, Heath Park, Cardiff, UK. Guy Van Vliet, MD, Staff Endocrinologist, CHU Sainte-Justine and Professor of Pediatrics, University of Montreal, Montreal, QC, Canada. Joseph I. Wolfsdorf, MB, BCh, MA, DCH, FCP, FAAP, Attending Physician in Endocrinology, Boston Children's Hospital Chair in Endocrinology, Professor of Pediatrics, Harvard Medical School, Boston, Massachusetts, U.S.A.

• Preface to the Fourth Edition ixAcknowledgements xiAbbreviations xiii1 Diabetes Mellitus 12 Hypoglycaemia 573 Short Stature 714 Tall Stature 1055 Puberty 1156 Thyroid Disorders 1437 Differences in Sex Development and Common Genital Anomalies 1698 Adrenal Disorders 1819 Salt and Water Balance 20310 Calcium and Bone 21711 Obesity 23512 Endocrine Effects of Cancer Treatment 247Supplementary chapter by Johnny Deladoëy13 An Endocrinologist’s Guide to Genetics in the Age of Genomics 257Appendix 1 Growth Charts and Body Mass Index (BMI) Charts 271Appendix 2 Syndrome-specific Growth Charts 287Appendix 3 Congenital Adrenal Hyperplasia (CAH) Therapy Card 299Index 301