Protocols for High-Risk Pregnancies

About the Editors JOHN T. QUEENAN, MD, Professor and Chairman Emeritus, Department of Obstetrics and Gynecology, Georgetown University School of Medicine, Washington, DC, USA. CATHERINE Y. SPONG, MD, is a Professor and Vice Chair in the Department of Obstetrics and Gynecology at University of Texas Southwestern Medical Center, Dallas, TX, USA. She also serves as Chief of the Department's Division of Maternal-Fetal Medicine. CHARLES J. LOCKWOOD, MD, MHCM, is Senior Vice President of USF Health, Dean of Morsani College of Medicine and a Professor of Obstetrics and Gynecology, and Public Health at the University of South Florida in Tampa, FL, USA.

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• Preface ixList of Contributors xiPart 1 Concerns in Pregnancy1 Alcohol Use in Pregnancy and Lactation 3Ruta M. Nonacs2 Smoking, Vaping, and Nicotine Exposure 9John Byrne and George Saade3 Opioid Use, Misuse, and Addiction in Pregnancy and Postpartum 15Mishka Terplan4 Depression 21Kimberly YonkersPart 2 Antenatal Testing5 Prenatal Testing for Chromosomal Abnormalities 29Mary E. Norton6 Fetal Echocardiography 41Joshua A. Copel7 Clinical Use of Doppler 49Henry L. Galan8 Antepartum Testing 61Michael P. Nageotte9 Fetal Blood Sampling and Transfusion 69Patricia Santiago‐Munoz10 Preconception Genetic Screening 77Lauren Sayres and Jeffrey A. KullerPart 3 Maternal Disease11 Maternal Anemia 89Elaine Duryea12 Hemoglobinopathies in Pregnancy 97Bradley Sipe and Judette Louis13 Fetal and Neonatal Alloimmune Thrombocytopenia 105Russell Miller and Richard Berkowitz14 Rheumatological Disorders 113Lisa R. Sammaritano and Bonnie L. Bermas15 Antiphospholipid Syndrome 125Robert M. Silver16 Inherited Thrombophilias 131Andra H. James and Jerome J. Federspiel17 Valvular Heart Disease in Pregnancy 141Blake Zwerling and Afshan B. Hameed18 Peripartum Cardiomyopathy 165Sarah Rae Easter and Carolyn M. Zelop19 Thromboembolism 181Michael J. Paidas20 Renal Disease 201Shivani Patel21 Obesity 209Patrick S. Ramsey22 Diabetes Mellitus 219Mark B. Landon and Steven G. Gabbe23 Thyroid Disorders 231Elizabeth O. Buschur and Stephen F. Thung24 Hepatitis in Pregnancy 241Andrew Myers, Asa Oxner, John Sinnott, and Christian Brechot25 Asthma 253Michael Schatz26 Epilepsy 263Thomas McElrath27 Chronic Hypertension 273Michal Fishel Bartal and Baha M. Sibai28 Cytomegalovirus, Genital Herpes, Rubella, and Toxoplasmosis 285Kerry E. Drury and Brenna L. Hughes29 Syphilis 293Emily H. Adhikari30 Vector‐Borne Diseases in Pregnancy: Zika, West Nile, and Chagas Disease 301Karin Nielsen‐Saines and Tara Kerin31 Influenza 317Amanda C. Zofkie and Vanessa Rogers32 Malaria 323Blair J. Wylie33 Human Immunodeficiency Virus Infection 333Emily H. Adhikari34 Parvovirus B19 343Kathy C. Matthews, Emilie L. Vander Haar, and Laura E. Riley35 Group B Streptococcus 351Caitlin A. MacGregor, and Mara J. Dinsmoor36 Biliary, Liver, and Pancreatic Disease 361Vic Velanovich, Elizabeth Hoover, and Stephanie RosPart 4 Obstetric Problems37 Cervical Insufficiency 375Rupsa C. Boelig and Vincenzo Berghella38 Nausea and Vomiting 387Jared T. Roeckner and Haywood L. Brown39 Fetal Death and Stillbirth 397Alexander M. Saucedo and Robert M. Silver40 Abnormal Amniotic Fluid Volume 407Christina M. Ackerman, Thomas R. Moore, and Heather S. Lipkind41 Fetal Growth Restriction 421Jodi S. Dashe and Anne M. Ambia42 Rh and Other Blood Group Alloimmunizations 431Kenneth J. Moise Jr43 Preterm Labor 443Hyagriv N. Simhan44 Prevention of Preterm Birth 449Anna King and Sarah J.E. Stock45 Premature Rupture of the Membranes 461Brian M. Mercer46 Indicated Late‐Preterm and Early‐Term Deliveries 475Catherine Y. Spong47 Chorioamnionitis 481Catalin S. Buhimschi and Irina A. Buhimschi48 Third‐Trimester Bleeding 493Ilina D. Pluym and Christina S. Han49 Amniotic Fluid Embolism 507Irene A. Stafford and Michael A. Belfort50 Preeclampsia 517Michal Fishel Bartal and Baha M. SibaiPart 5 Labor and Delivery51 Elective Induction of Labor 531Rachel G. Sinkey52 Electronic Fetal Heart Rate Monitoring 539David A. Miller53 Breech Delivery 555G. Justus Hofmeyr, and Mercy‐Nkuba Nassali54 Vaginal Birth After Cesarean 563James R. Scott55 Placenta Accreta Spectrum 571Robert M. Silver and Deirdre J. Lyell56 Shoulder Dystocia 581George A. Macones and Robert B. Gherman57 Twins, Triplets, and Beyond 587Mary E. D’Alton58 Postpartum Hemorrhage 601David B. NelsonAppendix A: Evaluation of Fetal Health and Defects 613Lynn L. SimpsonIndex 629