Fiona M. Lewis, MD, FRCP is a Consultant Dermatologist at the St. John's Institute of Dermatology, Guy's & St. Thomas' NHS Foundation Trust.

• List of Contributors xiPreface xiiiAcknowledgements xivAbout the Companion Website xvSection 1 The Basics of Vulval Disease 11 Vulval Embryology and Developmental Abnormalities 3Fiona M. Lewis2 The Normal Vulva 19Fiona M. Lewis3 Vulval Physiology and Changes Through Life 36Fiona M. Lewis4 Normal Microbiology of the Vulva 42Fiona M. Lewis5 The Vulval Clinic, History, and Examination 45Fiona M. Lewis6 Symptoms and Signs in Vulval Disease 51Fiona M. Lewis7 Investigations in Vulval Disease 56Fiona M. Lewis8 Topical and Non-Surgical Treatments 63Fiona M. LewisSection 2 Infection and the Vulva 699 Bacterial Vaginosis 71Gulshan Sethi10 Vulvovaginal Candidiasis 74Gulshan Sethi11 Syphilis 78Gulshan Sethi12 Gonorrhoea 83Gulshan Sethi13 Chlamydial Infection 87Gulshan Sethi14 Trichomoniasis 91Gulshan Sethi15 Genital Herpes 94Gulshan Sethi16 Human Papillomavirus Infections 99Gulshan Sethi17 Other Sexually Transmitted Infections 105Gulshan Sethi18 Tropical Infections 110Fiona M. Lewis19 Non-Sexually Transmitted Infections 117Fiona M. Lewis20 HIV Infection and Vulval Disease 129Gulshan SethiSection 3 Inflammatory Dermatoses 13121 Vulval Psoriasis 133Shireen Velangi22 Eczema and Allergic Reactions 139Fiona M. Lewis23 Lichen Sclerosus 147Fiona M. Lewis24 Lichen Planus 161Fiona M. Lewis25 Hidradenitis Suppurativa 171Ellie Rashidghamat26 Immunobullous Disease 180Elisabet Nylander27 Other Inflammatory Dermatoses 186Fiona M. LewisSection 4 Other Dermatological Conditions 19728 Genetic Conditions 199Fiona M. Lewis29 Disorders of Pigmentation 206Fiona M. Lewis30 Disorders of Skin Appendages and Hair 213Fiona M. Lewis31 Drug Reactions and the Vulva 217Fiona M. Lewis32 Conditions Associated with Systemic Disease 223Fiona M. Lewis33 Lymphatic Abnormalities and the Vulva 234Kristiana Gordon34 Vascular Abnormalities and the Vulva 240Fiona M. LewisSection 5 Vulvodynia 24335 Vulvodynia: History, Classification, and Terminology 245Nina Bohm-Starke and Ulrika Johannesson36 Vulvodynia: Pathophysiology and Clinical Features 248Nina Bohm-Starke and Ulrika Johannesson37 Vulvodynia: Management 260Nina Bohm-Starke and Ulrika JohannessonSection 6 Benign Tumours of the Vulva 26938 Benign Vulval Tumours 271Zlatko Marusic and Eduardo Calonje39 Benign Vulval Naevi 287Zlatko Marusic and Eduardo CalonjeSection 7 Intraepithelial Lesions 29140 High-Grade Squamous Intraepithelial Lesions 293Fabrizio Bogliatto and Fiona M. Lewis41 Differentiated Vulval Epithelial Neoplasia 301Fiona M. Lewis42 Vulval Paget's Disease 306Michelle van der LindenSection 8 Vulval Cancer 31343 Vulval Squamous Cell Carcinoma 315Marc van Beurden44 Malignant Melanoma of the Vulva 327Fiona M. Lewis45 Other Malignant Vulval Tumours 333Zlatko Marusic and Eduardo CalonjeSection 9 Surgical Procedures and Management of Other Conditions 34746 Female Genital Mutilation 349Refaat Karim47 Transgender Surgery and the Neovulva 355Fiona M. LewisSection 10 Psychological Aspects of Vulval Disease 35948 Psychological Aspects of Vulval Disorders 361Alia Ahmed and Fiona M. LewisSection 11 Vulval Disease in Children 37349 Inflammatory Dermatoses of the Vulva in Children 375Fiona M. Lewis50 Vulval Infection in Children 385Fiona M. Lewis51 Anatomical Abnormalities in Children 391Fiona M. Lewis52 Vulval Trauma in Children 396Fiona M. Lewis53 Vulval Lesions in Children 400Fiona M. LewisSection 12 Other Topics 40354 Vulval Trauma 405Fiona M. Lewis55 Cosmetic Procedures and Complications 412Fiona M. LewisGlossary of Terms 416Index 417

Fiona M. Lewis, MD, FRCP is a Consultant Dermatologist at the St. John's Institute of Dermatology, Guy's & St. Thomas' NHS Foundation Trust.

• List of Contributors xiPreface xiiiAcknowledgements xivAbout the Companion Website xvSection 1 The Basics of Vulval Disease 11 Vulval Embryology and Developmental Abnormalities 3Fiona M. Lewis2 The Normal Vulva 19Fiona M. Lewis3 Vulval Physiology and Changes Through Life 36Fiona M. Lewis4 Normal Microbiology of the Vulva 42Fiona M. Lewis5 The Vulval Clinic, History, and Examination 45Fiona M. Lewis6 Symptoms and Signs in Vulval Disease 51Fiona M. Lewis7 Investigations in Vulval Disease 56Fiona M. Lewis8 Topical and Non-Surgical Treatments 63Fiona M. LewisSection 2 Infection and the Vulva 699 Bacterial Vaginosis 71Gulshan Sethi10 Vulvovaginal Candidiasis 74Gulshan Sethi11 Syphilis 78Gulshan Sethi12 Gonorrhoea 83Gulshan Sethi13 Chlamydial Infection 87Gulshan Sethi14 Trichomoniasis 91Gulshan Sethi15 Genital Herpes 94Gulshan Sethi16 Human Papillomavirus Infections 99Gulshan Sethi17 Other Sexually Transmitted Infections 105Gulshan Sethi18 Tropical Infections 110Fiona M. Lewis19 Non-Sexually Transmitted Infections 117Fiona M. Lewis20 HIV Infection and Vulval Disease 129Gulshan SethiSection 3 Inflammatory Dermatoses 13121 Vulval Psoriasis 133Shireen Velangi22 Eczema and Allergic Reactions 139Fiona M. Lewis23 Lichen Sclerosus 147Fiona M. Lewis24 Lichen Planus 161Fiona M. Lewis25 Hidradenitis Suppurativa 171Ellie Rashidghamat26 Immunobullous Disease 180Elisabet Nylander27 Other Inflammatory Dermatoses 186Fiona M. LewisSection 4 Other Dermatological Conditions 19728 Genetic Conditions 199Fiona M. Lewis29 Disorders of Pigmentation 206Fiona M. Lewis30 Disorders of Skin Appendages and Hair 213Fiona M. Lewis31 Drug Reactions and the Vulva 217Fiona M. Lewis32 Conditions Associated with Systemic Disease 223Fiona M. Lewis33 Lymphatic Abnormalities and the Vulva 234Kristiana Gordon34 Vascular Abnormalities and the Vulva 240Fiona M. LewisSection 5 Vulvodynia 24335 Vulvodynia: History, Classification, and Terminology 245Nina Bohm-Starke and Ulrika Johannesson36 Vulvodynia: Pathophysiology and Clinical Features 248Nina Bohm-Starke and Ulrika Johannesson37 Vulvodynia: Management 260Nina Bohm-Starke and Ulrika JohannessonSection 6 Benign Tumours of the Vulva 26938 Benign Vulval Tumours 271Zlatko Marusic and Eduardo Calonje39 Benign Vulval Naevi 287Zlatko Marusic and Eduardo CalonjeSection 7 Intraepithelial Lesions 29140 High-Grade Squamous Intraepithelial Lesions 293Fabrizio Bogliatto and Fiona M. Lewis41 Differentiated Vulval Epithelial Neoplasia 301Fiona M. Lewis42 Vulval Paget's Disease 306Michelle van der LindenSection 8 Vulval Cancer 31343 Vulval Squamous Cell Carcinoma 315Marc van Beurden44 Malignant Melanoma of the Vulva 327Fiona M. Lewis45 Other Malignant Vulval Tumours 333Zlatko Marusic and Eduardo CalonjeSection 9 Surgical Procedures and Management of Other Conditions 34746 Female Genital Mutilation 349Refaat Karim47 Transgender Surgery and the Neovulva 355Fiona M. LewisSection 10 Psychological Aspects of Vulval Disease 35948 Psychological Aspects of Vulval Disorders 361Alia Ahmed and Fiona M. LewisSection 11 Vulval Disease in Children 37349 Inflammatory Dermatoses of the Vulva in Children 375Fiona M. Lewis50 Vulval Infection in Children 385Fiona M. Lewis51 Anatomical Abnormalities in Children 391Fiona M. Lewis52 Vulval Trauma in Children 396Fiona M. Lewis53 Vulval Lesions in Children 400Fiona M. LewisSection 12 Other Topics 40354 Vulval Trauma 405Fiona M. Lewis55 Cosmetic Procedures and Complications 412Fiona M. LewisGlossary of Terms 416Index 417