Transformation of Human Epithelial Cells (1992)

Molecular and Oncogenetic Mechanisms

AvGeorge Milo,Bruce Casto

Inbunden, Engelska, 2017

Del i serien CRC Press Revivals

3 752 kr

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Häftad

1 001 kr

Beskrivning

This book offers a conceptual explanation of the interrelationships that exist between the stages in the progression of initiated epithelial cells in culture compared with the diverse tissue of organs and the progression of tumors from different organ sites. The fate of the modification of adducts is discussed at the molecular level. The role that modifications in hot spots in oncogenes and supressor genes play at the molecular level and how these molecular modifications can lead to an explanation of molecular control in the formation of tumor phenotypes is also examined. Researchers in cell biology and toxicology, applied pharmacology, carcinogenesis, teratogenesis, mutagenesis, and molecular toxicology will find the book useful, interesting reading.

Produktinformation

Utgivningsdatum:2017-10-02
Mått:156 x 234 x 22 mm
Vikt:453 g
Format:Inbunden
Språk:Engelska
Serie:CRC Press Revivals
Antal sidor:326
Förlag:Taylor & Francis Ltd
ISBN:9781138105034

Utforska kategorier

Onkologi inom Medicin
Cellbiologi inom Naturvetenskap och teknik
Biologi inom Naturvetenskap och teknik

Mer om författaren

George Milo, Bruce Casto, Charles Shuler

Innehållsförteckning

In Vitro Cellular Aging and Immortalization. Detection of Growth Factor Effects and Expression in Normal and Neoplastic Human Bronchial Epithelial Cells. Human Cell Metabolism and DNA Adduction of Polycyclic Aromatic Hydrocarbons. Human Esophageal Epithelial Cells: Immortalization and In Vitro Transformation. Transformation of Human Endometrial Stromal Cells In Vitro. Factors Influencing Growth and Differentiation of Normal and Transformed Human Mammary Epithelial Cells in Culture. Transformation of Colon Epithelial Cells. Multistep Carcinogenesis and Human Epithelial Cells. Morphologic and Molecular Characterizations of Plastic Tumor Cell Phenotypes. Oncogene and Tumor Suppressor Gene Involvement in Human Lung Carcinogenesis. Events of Tumor Progression Associated with Carcinogen Treatment of Epithelial and Fibroblast Compared with Mutagenic Events. Progression from Pigment Cell Patterns to Melanomas in Platyfish-Swordtail Hybrids-Multiple Genetic Changes and a Theme for Tumorigenesis