J.N. Plevris MD, PhD, FRCP(E)Consultant Gastroenterologist & Senior Lecturer, Centre for Liver & Digestive Disorders, The Royal Infirmary of Edinburgh and Hepatology Laboratory, University of Edinburgh Medical School, Edinburgh, UKSubrata Ghosh MD (Edin) FRCP, FRCP (E)Gastrointestinal section, Imperial College School of Medicine, London, UK Colin W. Howden MD, PhDDivision of Gastroenterology, Northwestern University Feinberg School of Medicine, Chicago, USA

• Preface viiContributors viiiPart One Gastroenterology1 Dysphagia 3Nirmala Gonsalves, Ikuo Hirano, and John N. Plevris2 The Problem of Heartburn, and Atypical Chest Pain 17Ronnie Fass and Tiberiu Hershcovici3 The Clinical Approach to Dyspepsia 39Mary Farid and Brennan Spiegel4 Acute, Recurrent, and Chronic Abdominal Pain 44Brian E. Lacy and Chad C. Spangler5 Hematemesis, Melena, and Occult Bleeding/Anemia 64Grigorios I. Leontiadis and Virender K. Sharma6 Acute Diarrhea and Vomiting 72John P. Flaherty and Michael P. Angarone7 Chronic Diarrhea and Malabsorption 84Paul Beck, Remo Panaccione, and Subrata Ghosh8 Rectal Bleeding 96Matthew Shale, Lotte Dinesen, and Subrata Ghosh9 Multisystem Disorders and Gastrointestinal Disease 106Lynne A. Meekison and John N. PlevrisPart Two Hepatology and Pancreatobiliary10 Clinical Approach to Pancreatobiliary Disease 117Erica J. Revie, Lisa J. Massie, Anne-Marie Lennon, and O. James Garden11 The Problem of Right Upper Quadrant Pain 132Malcolm B. Barnes and Simon Glance12 Abnormal Liver Function Tests: Diagnostic Approach 144Timothy T. Gordon-Walker and John P. Iredale13 The Acute Liver Failure Patient 162Neil C. Henderson and Kenneth J. Simpson14 The Chronic Liver Disease Patient 174Joanna K. Dowman and Phil N. Newsome15 Portal Hypertension: A Management Problem 189Norma C. McAvoy and Peter C. Hayes16 Infections in the Liver 202Veerendra Sandur and George Therapondos17 The Liver Transplant Recipient 212Prakash Ramachandran and Andrew J. Bathgate18 Incidental Radiological Findings in the Asymptomatic Patient 226Tiffany J. Campbell and Dilip PatelIndex 241