• Fri frakt över 249 kr
  • •
  • Snabba leveranser
  • •
  • Billiga böcker
Kundservice

Du är på sajten för privatpersoner.

Företag, bibliotek eller offentlig verksamhet?

Du handlar på classic.bokus.com, där alla dina funktioner finns intakta.
Till classic.bokus.com
Bokus logotyp. Gå till startsidan.
  • Erbjudanden
  • Student
  • Topplistor
  • Barn & ungdom
  • Bokus Play
  • E-böcker
  • Ljudböcker
  • Pocketböcker
  • Spel och pussel

Skapa nya rutiner – hälsoböcker upp till 50% →

Sidfot

Mina sidor

    Hjälp

    • Kundservice
    • Vanliga frågor och svar
    • Frakt och leverans
    • Retur vid ångerrätt
    • Reklamera vara
    • Betalning
    • Köpvillkor
    • Allmänna villkor
    • Information om webbplatsens tillgänglighet

    Om Bokus

    • Om oss
    • Pressrum
    • För studenter
    • För företag
    • För bibliotek och offentlig verksamhet
    • För leverantörer
    • Hållbarhet

    Populärt

    • Aktuella erbjudanden
    • Presentkort
    • Studentlitteratur
    • Nya böcker
    • Topplistor
    • Signerade böcker
    • Engelska böcker

    Inspiration

    • Boktips
    • BookTok
    • Barnbokskaraktärer
    • Populära författare
    Logotyp för Bokus
    Följ oss på Facebook (extern länk)Följ oss på Instagram (extern länk)Följ oss på YouTube (extern länk)Följ oss på TikTok (extern länk)
    bokus @ CookiesAnpassa cookiesIntegritetspolicyKöpvillkor
    Till Citymail hemsida (extern länk)Till Budbee hemsida (extern länk)Till Postnord hemsida (extern länk)Till Schenker hemsida (extern länk)Till Early Bird hemsida (extern länk)Till Walleys hemsida (extern länk)
    1. Medicin
    2. Andra medicinska specialiteter
    3. Farmakologi

    Adrenal Toxicology

    AvPhilip W. Harvey,David J. Everett

    Inbunden, Engelska, 2008

    Del i serien Target Organ Toxicology Series

    3 036 kr

    Beställningsvara. Skickas inom 10-15 vardagar. Fri frakt över 249 kr.

    Beskrivning

    Despite being regarded as the most common toxicological target in the endocrine system, the adrenal gland has often been neglected in regulatory testing. Adrenal Toxicology addresses the increased interest in adrenocortical toxicology and the need for a resource that makes techniques available to examine adrenal endocrine disruption. Examining current techniques and the latest advancements, Adrenal Toxicology reviews the endocrinology, pharmacology, pathology and toxicology of the adrenal gland. This text provides information on the range of drugs and chemicals that affect adrenocortical function and suggests standardized approaches for in vivo and in vitro assessment. This volume also presents recent developments in the molecular mechanisms of toxicity to the adrenal cortex and medulla, and considers environmental adrenal endocrine disruption in sentinel species.Adrenal Toxicology: reflects the major developments made over the past decadefocuses on the latest research techniques, including their uses and limitationsprovides an integrated strategy for adrenal toxicology evaluationidentifies knowledge and data gaps, providing impetus for regulatory consideration

    Produktinformation

    • Utgivningsdatum:2008-10-22
    • Mått:152 x 229 x undefined mm
    • Vikt:810 g
    • Format:Inbunden
    • Språk:Engelska
    • Serie:Target Organ Toxicology Series
    • Antal sidor:338
    • Förlag:Taylor & Francis Inc
    • ISBN:9781420061291

    Utforska kategorier

    • Farmakologi inom Medicin
    • Endokrinologi inom Medicin
    • Veterinärmedicin inom Medicin

    Mer om författaren

    PHILIP W. HARVEY received his honors degree and doctorate (endocrine, reproductive/ developmental, and neurobehavioral toxicology) from the University of Keele, UK, and has worked in general industrial/pharmaceutical toxicology for over 20 years. He has particular interests in endocrine toxicology (the adrenal, prolactin and hormonal carcinogenesis, estrogenic chemicals and human health) and devised and edited the books The Adrenal in Toxicology: Target Organ and Modulator of Toxicity (1996) and Endocrine and Hormonal Toxicology (1999). He has served on various journal editorial boards and is currently the Editor-in-Chief of Journal of Applied Toxicology.DAVID J. EVERETT received his honors degree in biological sciences from the University of Sussex, UK, and has been actively involved in toxicological safety assessment of novel pharmaceuticals, agrochemicals and industrial chemicals for more than 30 years. His involvement in carcinogenicity has led to a particular interest for him in hormonal carcinogenesis. He is a Fellow of the Institute of Biology.CHRISTOPHER J. SPRINGALL is a toxicological pathologist who received his original medical degree from Liverpool University, UK, and has been actively involved in toxicology and drug development for over 25 years. He has worked with a very wide range of candidate drugs, including a substantial number which have an impact on endocrine systems.

    Innehållsförteckning

    • PART I - Introduction to adrenal toxicology. 1. Adrenal toxicology: Molecular targets, endocrine mechanisms, hormonal interactions, assessment models and species differences in toxicity. PART II - Hypothalamo-pituitary-adrenal pathophysiology, endocrinology and pharmacology. 2. An overview of human adrenal dysfunction. 3. The hypothalamo-pituitary-adrenocortical axis: Endocrinology, pharmacology, pathophysiology and developmental effects. PART III - Adrenal toxicology in vivo and in vitro. 4. The adrenal medulla as a target organ in toxicologic studies of rats and mice. 5. Adrenal gland background pathology of primates in toxicological studies. 6. Hypothalamic-pituitary-adrenal toxicity in dogs. 7. Adrenocortical toxicology in vitro: Assessment of steroidogenic enzyme expression and steroid production in H295R cells. 8. Comparisons of adrenocortical cell lines as in vitro test systems. 9. Glucocorticoid pharmacotoxicological interactions and modulation of toxicity. PART IV - Adrenal dysfunction in environmental sentinel species. 10. Adrenocortical toxicology in fishes. 11. Adrenocortical toxicology in birds: Environmental contaminants and the avian response to stress.
    Hoppa över listan

    Du kanske också är intresserad av

    Christopher J. Springall, David J. Everett, Philip W. Harvey - Adrenal Toxicology, E-bok

    Adrenal Toxicology

    Christopher J. Springall, David J. Everett, Philip W. Harvey

    E-bok
    2008

    3 428 kr

    J. Charles Eldridge, James T. Stevens - Endocrine Toxicology, Inbunden

    Endocrine Toxicology

    J. Charles Eldridge, James T. Stevens

    Inbunden, 2010

    2 113 kr

    Deborah K. Hansen, Barbara D. Abbott - Developmental Toxicology, Häftad

    Developmental Toxicology

    Deborah K. Hansen, Barbara D. Abbott

    Häftad, 2018

    1 002 kr

    Christopher J. Springall, David J. Everett, Philip W. Harvey - Adrenal Toxicology, E-bok

    Adrenal Toxicology

    Christopher J. Springall, David J. Everett, Philip W. Harvey

    E-bok
    2008

    3 419 kr

    Donald E. Gardner - Toxicology of the Lung, Inbunden

    Toxicology of the Lung

    Donald E. Gardner

    Inbunden, 2005

    3 036 kr

    Michael P. Waalkes, Jerrold M. Ward - Carcinogenesis, Inbunden

    Carcinogenesis

    Michael P. Waalkes, Jerrold M. Ward

    Inbunden, 1994

    1 815 kr

    Deborah K. Hansen, Barbara D. Abbott - Developmental Toxicology, Inbunden

    Developmental Toxicology

    Deborah K. Hansen, Barbara D. Abbott

    Inbunden, 2008

    3 206 kr

    Nancy A. Monteiro-Riviere - Toxicology of the Skin, Inbunden

    Toxicology of the Skin

    Nancy A. Monteiro-Riviere

    Inbunden, 2010

    3 036 kr

    John A. Thomas, Howard D. Colby - Endocrine Toxicology, Inbunden

    Endocrine Toxicology

    John A. Thomas, Howard D. Colby

    Inbunden, 1997

    2 036 kr

    Michael Denison, William Helferich - Toxicant-Receptor Interactions, Inbunden

    Toxicant-Receptor Interactions

    Michael Denison, William Helferich

    Inbunden, 1998

    1 706 kr