Polymorphism in Pharmaceutical Solids

Using clear and practical examples, Polymorphism of Pharmaceutical Solids, Second Edition presents a comprehensive examination of polymorphic behavior in pharmaceutical development that is ideal for pharmaceutical development scientists and graduate students in pharmaceutical science. This edition focuses on pharmaceutical aspects of polymorphism and solvatomorphism, while systematically explaining their thermodynamic and structural origins. Topics include: Computational methodologiesHigh-throughput screening methodsPharmaceutical cocrystalsThermally-induced and solution-mediated phase transformationsAmorphous solids Crystallography preparation and characterization The amorphous state