X. Allen Li

The authors have succeeded in creating a single compendium which covers nearly every aspect of this complex subject. There is a great need for such a book given the scope and variety of techniques involved, and the lack of any clear consensus on how to implement adaptive therapy regimes. … It is well laid out, with lots of diagrams, worked examples and case studies as well as referencing all the key documents on the subject. … an excellent one-stop resource for any centre considering implementing adaptive radiotherapy techniques. —Keri Owen, Scope, December 2011The breadth of the book is impressive, and the authors of each chapter provide a wealth of up-to-date references making it easy for readers who are interested in exploring certain ART techniques and technologies in more detail … The editor and the authors are to be commended for producing a valuable work on a very dynamic field that offers a chance for meaningful clinical benefits to many patients receiving radiation therapy for a variety of cancer types and clinical indications.—Moyed Miften, Ph.D., University of Colorado School of Medicine, Medical Physics The editor and authors are to be commended for putting together this excellent book describing the rationale, technologies, implementation, and future research for adaptive radiation therapy (ART). This topic is very timely as ART is the most logical approach to personalized medicine for cancer patients requiring radiation therapy as a single or combined modality treatment. The book contains a wealth of useful information ranging from practical workflow issues to directions of future research. I recommend this book for medical physicists and radiation oncologists who are interested in clinical practice and research utilizing advanced imaging and radiation therapy technology.—James C.H. Chu, Ph.D., Professor and Director of Medical Physics, Rush University Medical CenterDr. Li and his colleagues are to be commended for assembling within a single volume a compendium of recent vast technological progress that advances us towards this paramount goal [of individualized radiation therapy].—From the Foreword by J. Frank Wilson

• Treatment planning and delivery of physically and biologically adaptive radiation therapy: An introduction. Part I. Treatment Planning. Goals of radiation therapy. 3D and 4D Morphological imaging for radiation treatment planning. Biological Imaging for Radiation Treatment Planning. Biomarkers for early radiation response. Inverse treatment planning. Biologically-based models for treatment planning. Tumor Radiation Response assessment and feedback for treatment planning. Normal Tissue Radiation Response Assessment and Feedback for treatment planning. Part II. Treatment Delivery. IMRT delivery. CT-based IGRT technology. Non-CT based IGRT. Off-line Correction Strategies for interfraction variations. Online Correction strategies for interfraction variations. Intrafraction Variations and Management Technologies. Stereotactic radiation therapy delivery. Image-guide brachytherapy. Quality Assurance in Adaptive Radiation Therapy. Part III. Clinical Applications. Adaptive Radiation Therapy for Central Nervous System. Adaptive Radiation Therapy for Head and Neck. Adaptive Radiation therapy for Breast. Adaptive Radiation Therapy for Lung. Adaptive Radiation Therapy for Liver. Adaptive Radiation Therapy for Prostate. Adaptive Radiation Therapy for Sarcoma.

X. Allen Li

The authors have succeeded in creating a single compendium which covers nearly every aspect of this complex subject. There is a great need for such a book given the scope and variety of techniques involved, and the lack of any clear consensus on how to implement adaptive therapy regimes. … It is well laid out, with lots of diagrams, worked examples and case studies as well as referencing all the key documents on the subject. … an excellent one-stop resource for any centre considering implementing adaptive radiotherapy techniques. —Keri Owen, Scope, December 2011The breadth of the book is impressive, and the authors of each chapter provide a wealth of up-to-date references making it easy for readers who are interested in exploring certain ART techniques and technologies in more detail … The editor and the authors are to be commended for producing a valuable work on a very dynamic field that offers a chance for meaningful clinical benefits to many patients receiving radiation therapy for a variety of cancer types and clinical indications.—Moyed Miften, Ph.D., University of Colorado School of Medicine, Medical Physics The editor and authors are to be commended for putting together this excellent book describing the rationale, technologies, implementation, and future research for adaptive radiation therapy (ART). This topic is very timely as ART is the most logical approach to personalized medicine for cancer patients requiring radiation therapy as a single or combined modality treatment. The book contains a wealth of useful information ranging from practical workflow issues to directions of future research. I recommend this book for medical physicists and radiation oncologists who are interested in clinical practice and research utilizing advanced imaging and radiation therapy technology.—James C.H. Chu, Ph.D., Professor and Director of Medical Physics, Rush University Medical CenterDr. Li and his colleagues are to be commended for assembling within a single volume a compendium of recent vast technological progress that advances us towards this paramount goal [of individualized radiation therapy].—From the Foreword by J. Frank Wilson

• Treatment planning and delivery of physically and biologically adaptive radiation therapy: An introduction. Part I. Treatment Planning. Goals of radiation therapy. 3D and 4D Morphological imaging for radiation treatment planning. Biological Imaging for Radiation Treatment Planning. Biomarkers for early radiation response. Inverse treatment planning. Biologically-based models for treatment planning. Tumor Radiation Response assessment and feedback for treatment planning. Normal Tissue Radiation Response Assessment and Feedback for treatment planning. Part II. Treatment Delivery. IMRT delivery. CT-based IGRT technology. Non-CT based IGRT. Off-line Correction Strategies for interfraction variations. Online Correction strategies for interfraction variations. Intrafraction Variations and Management Technologies. Stereotactic radiation therapy delivery. Image-guide brachytherapy. Quality Assurance in Adaptive Radiation Therapy. Part III. Clinical Applications. Adaptive Radiation Therapy for Central Nervous System. Adaptive Radiation Therapy for Head and Neck. Adaptive Radiation therapy for Breast. Adaptive Radiation Therapy for Lung. Adaptive Radiation Therapy for Liver. Adaptive Radiation Therapy for Prostate. Adaptive Radiation Therapy for Sarcoma.

X. Allen Li

The authors have succeeded in creating a single compendium which covers nearly every aspect of this complex subject. There is a great need for such a book given the scope and variety of techniques involved, and the lack of any clear consensus on how to implement adaptive therapy regimes. … It is well laid out, with lots of diagrams, worked examples and case studies as well as referencing all the key documents on the subject. … an excellent one-stop resource for any centre considering implementing adaptive radiotherapy techniques. —Keri Owen, Scope, December 2011The breadth of the book is impressive, and the authors of each chapter provide a wealth of up-to-date references making it easy for readers who are interested in exploring certain ART techniques and technologies in more detail … The editor and the authors are to be commended for producing a valuable work on a very dynamic field that offers a chance for meaningful clinical benefits to many patients receiving radiation therapy for a variety of cancer types and clinical indications.—Moyed Miften, Ph.D., University of Colorado School of Medicine, Medical Physics The editor and authors are to be commended for putting together this excellent book describing the rationale, technologies, implementation, and future research for adaptive radiation therapy (ART). This topic is very timely as ART is the most logical approach to personalized medicine for cancer patients requiring radiation therapy as a single or combined modality treatment. The book contains a wealth of useful information ranging from practical workflow issues to directions of future research. I recommend this book for medical physicists and radiation oncologists who are interested in clinical practice and research utilizing advanced imaging and radiation therapy technology.—James C.H. Chu, Ph.D., Professor and Director of Medical Physics, Rush University Medical CenterDr. Li and his colleagues are to be commended for assembling within a single volume a compendium of recent vast technological progress that advances us towards this paramount goal [of individualized radiation therapy].—From the Foreword by J. Frank Wilson

• Treatment planning and delivery of physically and biologically adaptive radiation therapy: An introduction. Part I. Treatment Planning. Goals of radiation therapy. 3D and 4D Morphological imaging for radiation treatment planning. Biological Imaging for Radiation Treatment Planning. Biomarkers for early radiation response. Inverse treatment planning. Biologically-based models for treatment planning. Tumor Radiation Response assessment and feedback for treatment planning. Normal Tissue Radiation Response Assessment and Feedback for treatment planning. Part II. Treatment Delivery. IMRT delivery. CT-based IGRT technology. Non-CT based IGRT. Off-line Correction Strategies for interfraction variations. Online Correction strategies for interfraction variations. Intrafraction Variations and Management Technologies. Stereotactic radiation therapy delivery. Image-guide brachytherapy. Quality Assurance in Adaptive Radiation Therapy. Part III. Clinical Applications. Adaptive Radiation Therapy for Central Nervous System. Adaptive Radiation Therapy for Head and Neck. Adaptive Radiation therapy for Breast. Adaptive Radiation Therapy for Lung. Adaptive Radiation Therapy for Liver. Adaptive Radiation Therapy for Prostate. Adaptive Radiation Therapy for Sarcoma.