The Molecular Basis of Cancer

"This is a well-organized and well-written book that improves readers' understanding of the diverse mechanisms involved in cancer risk, growth, and treatments. The book provides a unique experience, uniting basic science with clinical applications to provide an integrated appreciation of the diverse molecular biology of cancer. It should be in the library of anyone interested in cancer research and treatment."-Karen L Reckamp, MD, MS(City of Hope) Doody Review: 4 stars2015 BMA Medical Book Awards: Highly Commended in Oncology

• The Molecular Basis of Cancer, 4eMendelsohn, Howley, Israel, Gray, ThompsonPart I: Carcinogenesis and Cancer Genetics 1. Cancer, A Genetic Disorder2. Oncogenes and Signal Transduction3. Tumor Suppressor Genes4. Genomic Instability and DNA Repair5. Epigenetics and Cancer6. Infectious Agents and Cancer7. Environmental Carcinogenesis8. Animal Models: Flies, Fish and Yeast 9. Genetic Mouse Models of CancerPart II: Cancer Biology 10. Cancer Stem Cells11. Regulation of the Cell Cycle 12. Cell Growth13. Cancer Cell Metabolism 14. Apoptosis, Autophagy and Necrosis15. Cell Growth Arrest and Senescence16. Stromal-Cancer Interactions in the Microenvironment17. Hypoxia and Angiogenesis18. Invasion and Metastasis19. Inflammation and Cancer20. Molecular Pathways and Systems BiologyPart III: Molecular Pathology and Diagnostics21. Biomarkers Assessing Risk of Cancer22. Biomarkers for Detecting Cancer: Molecular Screening23. Biomarkers for Predicting Response to Specific Therapy24. The Technology of Analyzing Nucleic Acids25. Imaging Cancer