Lymphocyte Development

Cell Selection Events and Signals During Immune Ontogeny

Häftad, Engelska, 2011

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Beskrivning

"Lymphocyte Development" presents an extremely up-to-date account of molecular processes involved in the development of lymphocytes. This well written book is based on a graduate course taught by the author. Topics include the selection processes involved in lymphocyte maturation, immune receptor gene rearrangement, signaling pathways involved in cell cycle progression and apoptosis, and the transcriptional regulation of lymphoid ontogeny. The book also covers T cell development and differentiation of helper and cytotoxic T cells as well as the development of Natural Killer lymphocytes. The book finishes with an account of the molecular basis of immunodeficiency syndromes. It will interest researchers in immunology and it will be useful as a supplementary text for a graduate level immunology course.

Produktinformation

Utgivningsdatum:2011-10-07
Mått:155 x 235 x 30 mm
Vikt:814 g
Format:Häftad
Språk:Engelska
Antal sidor:528
Förlag:Springer-Verlag New York Inc.
Medarbetare:D. Baltimore
ISBN:9781461275398

Utforska kategorier

Onkologi inom Medicin
Biologi inom Naturvetenskap och teknik

Innehållsförteckning

1 Overview of Cell Fate Decisions During Lymphoid Ontogeny.- 2 Commitment to a Lymphoid Fate.- 3 V(D)J Recombination and the Generation of Diversity.- 4 Pathways Mediating Signal Transduction and Cell Cycle Progression in Lymphocytes.- 5 Molecular Mechanisms of Lymphocyte Apoptosis.- 6 Lymphocyte Homing and the Generation of Secondary Lymphoid Organs.- 7 The Generation of Naive B Lymphocytes.- 8 Antigen-Induced B-Lymphocyte Differentiation.- 9 T Lymphocyte Development.- 10 The Activation and Differentiation of Mature T Lymphocytes.- 11 The Development of Natural Killer Cells.- 12 Naturally Occurring Disorders of Lymphocyte Development.