Natural Killer T cells

Balancing the Regulation of Tumor Immunity

AvMasaki Terabe,Jay A. Berzofsky

Inbunden, Engelska, 2011

Del i serien Cancer Drug Discovery and Development

1 093 kr

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Beskrivning

This book will cover primary roles of NKT cells in immunity to cancer, in both mouse tumor models and cancer patients. There are several chapters describing general aspects of NKT cells.

Produktinformation

Utgivningsdatum:2011-09-21
Mått:155 x 235 x 16 mm
Vikt:500 g
Format:Inbunden
Språk:Engelska
Serie:Cancer Drug Discovery and Development
Antal sidor:208
Upplaga:2012
Förlag:Springer-Verlag New York Inc.
ISBN:9781461406129

Utforska kategorier

Onkologi inom Medicin
Farmakologi inom Medicin

Recensioner i media

From the reviews: "This book is essentially a collection of reviews that introduce the reader to the wonderful world of iNKT cells, and how their powerful adjuvant properties are being utilised by different researchers. ... this book is worth reading whether you are a new student in the NKT field and want to learn more or whether you are a clinician with an interest in tumour immunology." (Salah Mansour, Immunology News, November, 2012)

Innehållsförteckning

Preface.- Introduction: Mechanisms of NKT cell-mediated adjuvant activity and function of iPS-derived NKT cells.- Structure and Recognition of Antigens for Invariant NKT Cells.- Invariant NKT cell-based vaccine strategies.- Immune regulation of tumor immunity by NKT cells.- The Regulation of CD1d+ and CD1d- tumors by NKT Cells.- DC-based immunotherapy targeting NKT cells.- Therapeutic Approaches Utilising NKT Cells.- NKT Cells of Cancer Patients & How Models can Inform Therapeutic Plans.- Understanding the role of Natural Killer T (NKT) cells in hematologic malignancies: progress and challenges.- Clinical trials with α-galactosylceramide (KRN7000) in advanced cancer.- Clinical trials of invariant Natural Killer T cell-based immunotherapy for cancer.- Index.