Insulin-like Growth Factors and Cancer

From Basic Biology to Therapeutics

AvDerek LeRoith

Häftad, Engelska, 2013

Del i serien Cancer Drug Discovery and Development

1 637 kr

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Beskrivning

The book will detail the history, successes, and failures of targeted therapies for cancer, with a particular focus on IGF systems and cancer.

Produktinformation

Utgivningsdatum:2013-10-24
Mått:155 x 235 x 17 mm
Vikt:452 g
Format:Häftad
Språk:Engelska
Serie:Cancer Drug Discovery and Development
Antal sidor:284
Upplaga:2012
Förlag:Springer-Verlag New York Inc.
ISBN:9781461429623

Utforska kategorier

Onkologi inom Medicin
Farmakologi inom Medicin

Innehållsförteckning

Preface.- Epidemiology of IGF-1 and Cancer.- Aging and Cancer: The IGF-I Connection.- Obesity, Type 2 Diabetes and Cancer.- IGF System and Breast Cancer.- The Role of Insulin-Like Growth Factor Signaling in Prostate Cancer Development and Progression.- Mouse Models of IGF-1 Deficiency.- Insulin-like Growth Factor Signaling in Pediatric Sarcomas.- Cancer Genes, Tumor Suppressors, and Regulation of IGF-1R Expression in Cancer.- Mouse Models of IGF-1R and Cancer.- Targeting the Insulin-Like Growth Factor-I Receptor in Cancer Therapy.- Targeting Insulin-like Growth Factor (IGF-1R) and Insulin Receptor Signaling by Tyrosine Kinase Inhibitors in Cancer.- Calories and Cancer: The Role of Insulin-like Growth Factor.- Cancer Cell Metabolism.- Overlaps between the Insulin and IGF-1R and Cancer.- Index

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