Advances in Human Genetics 10

AvHarry Harris

Häftad, Engelska, 2012

Del 10 i serien Advances in Human Genetics

572 kr

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E-bok

739 kr

Produktinformation

Utgivningsdatum:2012-01-24
Mått:152 x 229 x 23 mm
Vikt:600 g
Format:Häftad
Språk:Engelska
Serie:Advances in Human Genetics
Antal sidor:394
Förlag:Springer-Verlag New York Inc.
ISBN:9781461582908

Utforska kategorier

Medicinsk genetik inom Medicin

Innehållsförteckning

1 Biochemistry and Genetics of the ABO, Lewis, and P Blood Group Systems.- The ABO System.- The Lewis System.- The P System.- Serology and Genetics.- Chemistry of P1, P, and Pk Determinants.- Biosynthetic Pathways.- Relationship between ABH and P Systems.- Concluding Remarks.- References.- 2 HLA—A Central Immunological Agency of Man.- HLA: A Supergene.- HLA Terminology.- Inheritance of HLA.- The HLA-A, -B, and -C Allelic Series of Antigens.- HLA-D.- Cell-Mediated Lympholysis (CML).- HLA-DR.- Population Genetics.- The HLA “Supergene” and Transplantation.- Evolution and Maintenance of the MHC—Function?.- What of the Future?.- References.- 3 Linkage Analysis in Man.- General Considerations.- Historical Perspective.- Approach to Family Studies.- Preparation of Data Prior to Analysis.- Analysis of Data.- Interpretation of Results.- Multipoint Mapping.- Significance of Linkage.- References.- 4 Sister Chromatid Exchanges.- BrdUrd Methodology for SCE Detection.- Basic Information about SCEs.- Induction of Sister Chromatid Exchange by Clastogens.- Extension of SCE Studies from in Vitro to in Vivo Systems.- Interpretation of SCE Induction Tests.- Relationship of SCE Induction to DNA Damage, Repair, and Synthesis.- Relationship of SCE Induction to Mutagenesis.- Sister Chromatid Differentiation in Meiotic Cells.- Sister Chromatid Exchange Formation in Heritable Human Diseases.- Studies of the Mechanism of SCE Formation.- References.- 5 Genetic Disorders of Male Sexual Differentiation.- Normal Male Sex Differentiation in the Fetus.- Abnormal Male Sex Differentiation.- References.- Addenda.

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Advances in Human Genetics 10

AvHarry Harris

Häftad, Engelska, 2012

Del 10 i serien Advances in Human Genetics

572 kr

Beställningsvara. Skickas inom 10-15 vardagar. Fri frakt över 249 kr.

Fler format och utgåvor

E-bok

739 kr

Produktinformation

Utgivningsdatum:2012-01-24
Mått:152 x 229 x 23 mm
Vikt:600 g
Format:Häftad
Språk:Engelska
Serie:Advances in Human Genetics
Antal sidor:394
Förlag:Springer-Verlag New York Inc.
ISBN:9781461582908

Utforska kategorier

Medicinsk genetik inom Medicin

Innehållsförteckning

1 Biochemistry and Genetics of the ABO, Lewis, and P Blood Group Systems.- The ABO System.- The Lewis System.- The P System.- Serology and Genetics.- Chemistry of P1, P, and Pk Determinants.- Biosynthetic Pathways.- Relationship between ABH and P Systems.- Concluding Remarks.- References.- 2 HLA—A Central Immunological Agency of Man.- HLA: A Supergene.- HLA Terminology.- Inheritance of HLA.- The HLA-A, -B, and -C Allelic Series of Antigens.- HLA-D.- Cell-Mediated Lympholysis (CML).- HLA-DR.- Population Genetics.- The HLA “Supergene” and Transplantation.- Evolution and Maintenance of the MHC—Function?.- What of the Future?.- References.- 3 Linkage Analysis in Man.- General Considerations.- Historical Perspective.- Approach to Family Studies.- Preparation of Data Prior to Analysis.- Analysis of Data.- Interpretation of Results.- Multipoint Mapping.- Significance of Linkage.- References.- 4 Sister Chromatid Exchanges.- BrdUrd Methodology for SCE Detection.- Basic Information about SCEs.- Induction of Sister Chromatid Exchange by Clastogens.- Extension of SCE Studies from in Vitro to in Vivo Systems.- Interpretation of SCE Induction Tests.- Relationship of SCE Induction to DNA Damage, Repair, and Synthesis.- Relationship of SCE Induction to Mutagenesis.- Sister Chromatid Differentiation in Meiotic Cells.- Sister Chromatid Exchange Formation in Heritable Human Diseases.- Studies of the Mechanism of SCE Formation.- References.- 5 Genetic Disorders of Male Sexual Differentiation.- Normal Male Sex Differentiation in the Fetus.- Abnormal Male Sex Differentiation.- References.- Addenda.