Analysis of Macrophage Differentiation and Function with Monoclonal Antibodies.- Alterations of Surface Properties by Macrophage Activation: Expression of Receptors for Fc and Mannose-Terminal Glycoproteins and Differentiation Antigens.- Activation of Macrophage Complement Receptors for Phagocytosis.- Mechanisms of Microbial Entry and Endocytosis by Mononuclear Phagocytes.- Macrophage Activation: Enhanced Oxidative and Antiprotozoal Activity.- Activation of Mononuclear Phagocytes for the Destruction of Intracellular Parasites: Studies with Trypanosoma cruzi.- Expression and Development of Macrophage Activation for Tumor Cytotoxicity.- Activation of Macrophages to Kill Rickettsiae and Leishmania: Dissociation of Intracellular Microbicidal Activities and Extracellular Destruction of Neoplastic and Helminth Targets.- Identification of Gamma-Interferon as a Murine Macrophage-Activating Factor for Tumor Cytotoxicity.- Possible Autoregulatory Functions of the Secretory Products of Mononuclear Phagocytes.- Surveillance Role of Various Leukocytes in Preventing the Outgrowth of Potentially Malignant Cells.- Models of Adoptive T-Cell-Mediated Regression of Established Tumors.
