Edited byRichard W. Light, MD, FCCP, professor of medicine, Vanderbilt University, Nashville, Tennessee, USA, and Gaziantep University, TurkeyY. C. Gary Lee, MBChB, PhD, FRACP, FRCP, FCCP, professor of respiratory medicine, University of Western Australia; director of pleural services, Sir Charles Gairdner Hospital; and Queen Elizabeth II Medical Centre, Perth, Australia

"...a classic that has been updated with an excellent third edition... an important book for practitioners and scientists in the field and should be in every academic library." © Doody’s Review Service, 2016, 4* by Michael Bates, MD (Ochsner Medical Center)

• Pleural Diseases: Historic Perspective. BASIC SCIENCE. Pleural Embryology and Gross Structure, Circulation, Lymphatics, and Nerves. Mesothelial Cells and Pleural Immunology. Normal Physiological Fluid and Cellular Contents. Fluid and Solute Exchange in Normal and Disease States. Pleural Inflammation. Pleural Fibrosis. Genetics of Mesothelioma. Transcriptomics and Proteomics in Pleural Diseases. Pleural Pharmacokinetics. Experimental Models: Pleural Disease. CLINICAL SCIENCE. Approach to Patients with Pleural Diseases. Pleural Fluid Analysis. Pleural Manometry. Radiology: Diagnostic. Radiology: Interventional. Radiology: Pleural Ultrasound. Radiology: Nuclear Imaging. Pleural Histology. Pleural Fluid Cytology. Effusions from Cardiovascular Diseases. Effusion from Malignant Causes. Effusions from Infections: Parapneumonic Pleural Effusion and Empyema. Effusions from Infections: Tuberculosis. Effusions from Atypical Infections. Effusions Due to Lymphatic Disruption. Effusions in Immunocompromised Hosts. Effusions from Connective Tissue Diseases. Effusions Caused by Drugs. Effusions after Surgery. Effusions from Hepatic Hydrothorax. Effusions Caused by Gastrointestinal Disease. Effusions Associated with Gynecologic and Obstetric Conditions. Other Uncommon Pleural Effusions. Solitary Fibrous Tumors of the Pleura. Undiagnosed Pleural Effusions. Asbestos-Related Pleural Diseases. Mesothelioma. Spontaneous Pneumothorax. Non-Spontaneous Pneumothorax. Pleural Effusions in Pediatric Patients. Pleural Procedural Complications and Safety Measures. Drainage Techniques. Pleurodesis. Tunneled Pleural Catheters. Medical Thoracoscopy. Surgery for Pleural Diseases. Gene Therapy in Pleural Diseases. Setting up a Pleural Practice. Future Directions in Pleural Disease.

Edited byRichard W. Light, MD, FCCP, professor of medicine, Vanderbilt University, Nashville, Tennessee, USA, and Gaziantep University, TurkeyY. C. Gary Lee, MBChB, PhD, FRACP, FRCP, FCCP, professor of respiratory medicine, University of Western Australia; director of pleural services, Sir Charles Gairdner Hospital; and Queen Elizabeth II Medical Centre, Perth, Australia

"...a classic that has been updated with an excellent third edition... an important book for practitioners and scientists in the field and should be in every academic library." © Doody’s Review Service, 2016, 4* by Michael Bates, MD (Ochsner Medical Center)

• Pleural Diseases: Historic Perspective. BASIC SCIENCE. Pleural Embryology and Gross Structure, Circulation, Lymphatics, and Nerves. Mesothelial Cells and Pleural Immunology. Normal Physiological Fluid and Cellular Contents. Fluid and Solute Exchange in Normal and Disease States. Pleural Inflammation. Pleural Fibrosis. Genetics of Mesothelioma. Transcriptomics and Proteomics in Pleural Diseases. Pleural Pharmacokinetics. Experimental Models: Pleural Disease. CLINICAL SCIENCE. Approach to Patients with Pleural Diseases. Pleural Fluid Analysis. Pleural Manometry. Radiology: Diagnostic. Radiology: Interventional. Radiology: Pleural Ultrasound. Radiology: Nuclear Imaging. Pleural Histology. Pleural Fluid Cytology. Effusions from Cardiovascular Diseases. Effusion from Malignant Causes. Effusions from Infections: Parapneumonic Pleural Effusion and Empyema. Effusions from Infections: Tuberculosis. Effusions from Atypical Infections. Effusions Due to Lymphatic Disruption. Effusions in Immunocompromised Hosts. Effusions from Connective Tissue Diseases. Effusions Caused by Drugs. Effusions after Surgery. Effusions from Hepatic Hydrothorax. Effusions Caused by Gastrointestinal Disease. Effusions Associated with Gynecologic and Obstetric Conditions. Other Uncommon Pleural Effusions. Solitary Fibrous Tumors of the Pleura. Undiagnosed Pleural Effusions. Asbestos-Related Pleural Diseases. Mesothelioma. Spontaneous Pneumothorax. Non-Spontaneous Pneumothorax. Pleural Effusions in Pediatric Patients. Pleural Procedural Complications and Safety Measures. Drainage Techniques. Pleurodesis. Tunneled Pleural Catheters. Medical Thoracoscopy. Surgery for Pleural Diseases. Gene Therapy in Pleural Diseases. Setting up a Pleural Practice. Future Directions in Pleural Disease.

Edited byRichard W. Light, MD, FCCP, professor of medicine, Vanderbilt University, Nashville, Tennessee, USA, and Gaziantep University, TurkeyY. C. Gary Lee, MBChB, PhD, FRACP, FRCP, FCCP, professor of respiratory medicine, University of Western Australia; director of pleural services, Sir Charles Gairdner Hospital; and Queen Elizabeth II Medical Centre, Perth, Australia

"...a classic that has been updated with an excellent third edition... an important book for practitioners and scientists in the field and should be in every academic library." © Doody’s Review Service, 2016, 4* by Michael Bates, MD (Ochsner Medical Center)

• Pleural Diseases: Historic Perspective. BASIC SCIENCE. Pleural Embryology and Gross Structure, Circulation, Lymphatics, and Nerves. Mesothelial Cells and Pleural Immunology. Normal Physiological Fluid and Cellular Contents. Fluid and Solute Exchange in Normal and Disease States. Pleural Inflammation. Pleural Fibrosis. Genetics of Mesothelioma. Transcriptomics and Proteomics in Pleural Diseases. Pleural Pharmacokinetics. Experimental Models: Pleural Disease. CLINICAL SCIENCE. Approach to Patients with Pleural Diseases. Pleural Fluid Analysis. Pleural Manometry. Radiology: Diagnostic. Radiology: Interventional. Radiology: Pleural Ultrasound. Radiology: Nuclear Imaging. Pleural Histology. Pleural Fluid Cytology. Effusions from Cardiovascular Diseases. Effusion from Malignant Causes. Effusions from Infections: Parapneumonic Pleural Effusion and Empyema. Effusions from Infections: Tuberculosis. Effusions from Atypical Infections. Effusions Due to Lymphatic Disruption. Effusions in Immunocompromised Hosts. Effusions from Connective Tissue Diseases. Effusions Caused by Drugs. Effusions after Surgery. Effusions from Hepatic Hydrothorax. Effusions Caused by Gastrointestinal Disease. Effusions Associated with Gynecologic and Obstetric Conditions. Other Uncommon Pleural Effusions. Solitary Fibrous Tumors of the Pleura. Undiagnosed Pleural Effusions. Asbestos-Related Pleural Diseases. Mesothelioma. Spontaneous Pneumothorax. Non-Spontaneous Pneumothorax. Pleural Effusions in Pediatric Patients. Pleural Procedural Complications and Safety Measures. Drainage Techniques. Pleurodesis. Tunneled Pleural Catheters. Medical Thoracoscopy. Surgery for Pleural Diseases. Gene Therapy in Pleural Diseases. Setting up a Pleural Practice. Future Directions in Pleural Disease.