Alberto d'Onofrio is the Research Group-Leader TT in the Department of Experimental Oncology at European Institute of Oncology, Milan, Italy Alberto Gandolfi is the Research Director of the Mathematical Modeling in Biology and Medicine at the Institute of Systems Analysis and Computer Science "Antonio Ruberti", Milan, Italy.

• Part I: Cancer Onset and Early Growth.- Modeling spatial effects in carcinogenesis: stochastic and deterministic reaction-diffusion.- Conservation law in cancer modeling.- Avascular tumor growth modeling: physical insight in skin cancer.- Part II: Tumor and Inter-Cellular Interactions.- A cell population model structured by cell age incorporating cell-cell adhesion.- A general framework for multiscale modeling of tumor–immune system interactions.- The power of the tumor microenvironment: a systemic approach for a systemic disease.- Part III: Anti-Tumor Therapies.- Modeling immune-mediated tumor growth and treatment.- Hybrid multiscale approach in cancer modelling and treatment prediction.- Deterministic mathematical modelling for cancer chronotherapeutics: cell population dynamics and treatment optimization.- Tumor Microenvironment and Anticancer Therapies: An Optimal Control Approach.

Alberto d'Onofrio is the Research Group-Leader TT in the Department of Experimental Oncology at European Institute of Oncology, Milan, Italy Alberto Gandolfi is the Research Director of the Mathematical Modeling in Biology and Medicine at the Institute of Systems Analysis and Computer Science "Antonio Ruberti", Milan, Italy.

• Part I: Cancer Onset and Early Growth.- Modeling spatial effects in carcinogenesis: stochastic and deterministic reaction-diffusion.- Conservation law in cancer modeling.- Avascular tumor growth modeling: physical insight in skin cancer.- Part II: Tumor and Inter-Cellular Interactions.- A cell population model structured by cell age incorporating cell-cell adhesion.- A general framework for multiscale modeling of tumor–immune system interactions.- The power of the tumor microenvironment: a systemic approach for a systemic disease.- Part III: Anti-Tumor Therapies.- Modeling immune-mediated tumor growth and treatment.- Hybrid multiscale approach in cancer modelling and treatment prediction.- Deterministic mathematical modelling for cancer chronotherapeutics: cell population dynamics and treatment optimization.- Tumor Microenvironment and Anticancer Therapies: An Optimal Control Approach.

Alberto d'Onofrio is the Research Group-Leader TT in the Department of Experimental Oncology at European Institute of Oncology, Milan, Italy Alberto Gandolfi is the Research Director of the Mathematical Modeling in Biology and Medicine at the Institute of Systems Analysis and Computer Science "Antonio Ruberti", Milan, Italy.

• Part I: Cancer Onset and Early Growth.- Modeling spatial effects in carcinogenesis: stochastic and deterministic reaction-diffusion.- Conservation law in cancer modeling.- Avascular tumor growth modeling: physical insight in skin cancer.- Part II: Tumor and Inter-Cellular Interactions.- A cell population model structured by cell age incorporating cell-cell adhesion.- A general framework for multiscale modeling of tumor–immune system interactions.- The power of the tumor microenvironment: a systemic approach for a systemic disease.- Part III: Anti-Tumor Therapies.- Modeling immune-mediated tumor growth and treatment.- Hybrid multiscale approach in cancer modelling and treatment prediction.- Deterministic mathematical modelling for cancer chronotherapeutics: cell population dynamics and treatment optimization.- Tumor Microenvironment and Anticancer Therapies: An Optimal Control Approach.