Prof. Robert Weissert, M.D. Ph.D. University Professor of Clinical Neurobiology Department of Neurology University of Regensburg Universitätsstraße 84 93053 Regensburg Germany Phone: +49-941-9418721 E-mail: robert.weissert@klinik.uni-regensburg.de

• Positional Gene Cloning in Experimental Populations.- Generation of Transgenic Rats Using Lentiviral Vectors.- DNA Vaccination Techniques.- Peripheral Blood Mononuclear Cells: Isolation, Freezing, Thawing, and Culture.- ELISPOT Techniques.- Isolation of Central Nervous System (CNS) Infiltrating Cells.- Methods for Ex Vivo Analysis of Immune Cell Function from the Central Nervous System.- Neurofilament Light Chain Determination from Peripheral Blood Samples.- Detection of Autoantibodies Against Myelin Oligodendrocyte Glycoprotein in Multiple Sclerosis and Related Diseases.- Myelinating Cultures: An In Vitro Tool to Identify Demyelinating and Axopathic Autoantibodies.- In Vivo Visualization of (Auto-) Immune Processes in the Central Nervous System of Rodents.- Optical Coherence Tomography to Assess Neurodegeneration in Multiple Sclerosis.- Experimental Autoimmune Encephalomyelitis in Mice.- Actively Induced Experimental Autoimmune Encephalomyelitis in Rats.- Experimental Autoimmune Encephalomyelitis in Marmosets.- Neuropathological Techniques to Investigate CNS Pathology in Experimental Autoimmune Encephalomyelitis (EAE).- Neuropathological Techniques to Investigate Central Nervous System Sections in Multiple Sclerosis.

Prof. Robert Weissert, M.D. Ph.D. University Professor of Clinical Neurobiology Department of Neurology University of Regensburg Universitätsstraße 84 93053 Regensburg Germany Phone: +49-941-9418721 E-mail: robert.weissert@klinik.uni-regensburg.de

• Positional Gene Cloning in Experimental Populations.- Generation of Transgenic Rats Using Lentiviral Vectors.- DNA Vaccination Techniques.- Peripheral Blood Mononuclear Cells: Isolation, Freezing, Thawing, and Culture.- ELISPOT Techniques.- Isolation of Central Nervous System (CNS) Infiltrating Cells.- Methods for Ex Vivo Analysis of Immune Cell Function from the Central Nervous System.- Neurofilament Light Chain Determination from Peripheral Blood Samples.- Detection of Autoantibodies Against Myelin Oligodendrocyte Glycoprotein in Multiple Sclerosis and Related Diseases.- Myelinating Cultures: An In Vitro Tool to Identify Demyelinating and Axopathic Autoantibodies.- In Vivo Visualization of (Auto-) Immune Processes in the Central Nervous System of Rodents.- Optical Coherence Tomography to Assess Neurodegeneration in Multiple Sclerosis.- Experimental Autoimmune Encephalomyelitis in Mice.- Actively Induced Experimental Autoimmune Encephalomyelitis in Rats.- Experimental Autoimmune Encephalomyelitis in Marmosets.- Neuropathological Techniques to Investigate CNS Pathology in Experimental Autoimmune Encephalomyelitis (EAE).- Neuropathological Techniques to Investigate Central Nervous System Sections in Multiple Sclerosis.

Prof. Robert Weissert, M.D. Ph.D. University Professor of Clinical Neurobiology Department of Neurology University of Regensburg Universitätsstraße 84 93053 Regensburg Germany Phone: +49-941-9418721 E-mail: robert.weissert@klinik.uni-regensburg.de

• Positional Gene Cloning in Experimental Populations.- Generation of Transgenic Rats Using Lentiviral Vectors.- DNA Vaccination Techniques.- Peripheral Blood Mononuclear Cells: Isolation, Freezing, Thawing, and Culture.- ELISPOT Techniques.- Isolation of Central Nervous System (CNS) Infiltrating Cells.- Methods for Ex Vivo Analysis of Immune Cell Function from the Central Nervous System.- Neurofilament Light Chain Determination from Peripheral Blood Samples.- Detection of Autoantibodies Against Myelin Oligodendrocyte Glycoprotein in Multiple Sclerosis and Related Diseases.- Myelinating Cultures: An In Vitro Tool to Identify Demyelinating and Axopathic Autoantibodies.- In Vivo Visualization of (Auto-) Immune Processes in the Central Nervous System of Rodents.- Optical Coherence Tomography to Assess Neurodegeneration in Multiple Sclerosis.- Experimental Autoimmune Encephalomyelitis in Mice.- Actively Induced Experimental Autoimmune Encephalomyelitis in Rats.- Experimental Autoimmune Encephalomyelitis in Marmosets.- Neuropathological Techniques to Investigate CNS Pathology in Experimental Autoimmune Encephalomyelitis (EAE).- Neuropathological Techniques to Investigate Central Nervous System Sections in Multiple Sclerosis.