Bacteriophage Therapy

From Lab to Clinical Practice

AvJoana Azeredo,Sanna Sillankorva

Inbunden, Engelska, 2017

Del i serien Methods in Molecular Biology

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Beskrivning

This volume details the experimental approaches suitable for isolating and characterizing bacteriophages to formulating bacteriophage medicinal products and clinical application.

Produktinformation

Utgivningsdatum:2017-11-27
Mått:178 x 254 x 24 mm
Vikt:778 g
Format:Inbunden
Språk:Engelska
Serie:Methods in Molecular Biology
Antal sidor:303
Förlag:Humana Press Inc.
ISBN:9781493973941

Utforska kategorier

Biologi inom Naturvetenskap och teknik

Innehållsförteckning

Isolation of Bacteriophages for Fastidious Bacteria.- Isolation of Bacteriophages of the Anaerobic Bacteria Bacteroides.- Isolation of Bacteriophages for Clinically Relevant Bacteria.- In Vitro Activity against Planktonic and Biofilm Populations Assessed by Flow Cytometry.- Observation of Bacteriophage Ultrastructure by Cryo-electron Microscopy.- Bacteriophage Taxonomy: an Evolving Discipline.- Determination of the Bacteriophage Host Range – Culture Based Approach.- Recovery and Characterization of Bacteria Resisting Infection by Lytic Bacteriophage.- Guidelines to Compose an Ideal Bacteriophage Cocktail.- Interaction of Bacteriophages with Mammalian Cells.- In Vivo Bacteriophage Biodistribution.- Interaction of Bacteriophages with the Immune System: Induction of Bacteriophage-specific Antibodies.- Bacteriophage Treatment of Infected Diabetic Foot Ulcers.- Compassionate Use of Bacteriophage Therapy for Foot Ulcer Treatment as an Effective Step for Moving Toward Clinical Trials.- Bacteriophage Production in Bioreactors.- Computational Modelling of Bacteriophage Production for Process Optimization.- Methods for Bacteriophage Preservation.- Bacteriophage Production in Compliance with Regulatory Requirements.- Guidelines for Bacteriophage Product Certification.- Nano/micro Formulations for Bacteriophage Delivery.- Synthetic Biology to Engineer Bacteriophage Genomes.