From Local Invasion to Metastatic Cancer

From the reviews: 4 Stars "Provides highlights from a state-of-the art symposium on mechanisms of metastases, thus bringing together the best thinking in the field... The book is written for specialists -- medical, surgical, or radiation oncologists -- or basic scientists working in the field. For others, it will be a useful reference... It is well illustrated and includes color illustrations... This is an excellent contribution to the field. It occupies a unique niche and will fill a gap in the literature. It should find a place in libraries and on the shelves of specialists." (Carol Scott-Conner, MD, PhD, Doody's Review Service, September 2009)

• Innovation and Experience.- Frontiers of Cancer Research: The Metastasis Challenge.- Vascular Endothelial Growth Factor: Basic Biology and Clinical Applications.- Proliferation and Cancer Metastasis from the Clinical Point of View.- Gastrointestinal Cancer and the Lymphatic System: Patterns of Micrometastasis and Lymphatic Mapping with Clinical Outcome.- Redefined Lymphatic Anatomy of the Breast with Clinical Implications.- Should Axillary Lymph Node Dissection be Done for Breast Cancer?.- Tumor Microenvironment and Proliferation.- Overview of Tumor Cells and the Microenvironment.- Lymphangiogenesis and Angiogenesis.- Heme/Lymphvasculogenesis, Hem/Lymphangiogenesis, Hem/Lymphangiotumorigenesis, and Tumor Hem/Lymphangiogenesis: Need for a Terminology Adjustment.- Tumor Lymphangiogenesis: What We Know and Don't Know.- Diagnostic Imaging of Cancer.- Molecular Imaging of Cancer: Receptors, Angiogenesis, and Gene Expression.- MRI and Ultrasound Imaging of Lymph Nodes.- Molecular Imaging of the Sentinel Lymph Node via Lymphoseek.- Lymphatic Disorders in Patients with Cancer.- 3D-CT Lymphography for Mapping Metastatic Breast Sentinel Node and Axillary Nodes.- Molecular Imaging of Neuroendocrine Cancer by Fusion SPET/CT.- Functional Molecular Imaging of Prostate Cancer Lymph Node Metastases: Adenovirus-Mediated Lymph Node Detection.- Therapeutic Targeting of the Lymphovascular System.- Therapeutic Targeting of the Lymphovascular System in Cancer: Promise and Challenge.- Comparison of Liposomal and Aqueous Blue Dye in Visualization of Lymph Nodes Prior to Lymphadenectomy.- Molecular Mechanisms of Metastasis.- The Role of Lymphangiogenesis in Regional Lymph Node Metastasis: Animal Models.- Sentinel Lymph Node Chemokine Microenvironment Modulated by Melanoma Metastasis.- Circulating and Disseminated Tumor Cells from Solid Tumors—Research and Clinical Aspects.- Head and Neck Cancer: An Example for the Role of Chemokine Receptors in Tumor Progression and Metastasis.- Tumor and Lymph Node Lymphangiogenesis.- Treg, Chemokines, and Other Small Molecules: Role in Metastasis and Its Prevention.- Molecular Targeted Therapy Against Growth Factor Receptors, Signaling Pathways and Angiogenesis as Therapeutic Targets.- Molecular Targeting of Lymphangiogenesis and Tumor Metastasis.- Combined Targeting of EGFR and Angiogenesis in Aerodigestive Carcinomas.- Targeting Signaling Pathways in Cancer Therapy.- Impact of Nodal Status and Tumor Burden in Sentinel Nodes on the Clinical Outcome.- Micrometastasis of Melanoma to Sentinel Lymph Nodes.- Sentinel Lymph Node Micrometastases in Breast Cancer: Prognostic Relevance and Therapeutic Implications.- Micrometastasis of Genitourinary Cancer to Sentinel Lymph Nodes.- Sentinel Lymph Node Mapping in Colorectal Cancer.- Application of Cancer Biology in Cancer Staging and Predicting Clinical Outcome.- Immune Responses in the Draining Lymph Nodes Against Cancer: Implication for Immunotherapy.- Role of Lymph Nodes in Immunotherapy of Malignant Tumors.- Tumor-Related Immune Modulation of the Regional Lymph Nodes.- Reversal of Immune Suppression in Sentinel Lymph Nodes.- Vaccine-Primed Lymph Node Cells in the Adoptive Immunotherapy of Cancer: Presence of Host Immune Suppression Induced by Established Cancer.- The Role of Stem Cells in Cancer Metastasis.- Cancer Stem Cells in Metastatic Melanoma.- Implications of Cancer Stem Cells for Tumor Metastasis.- Prostate Cancer Stem Cells and Their Involvement in Metastasis.- Genomic Signatures of Cancer: Basis for Selective Adjuvant Therapy.- Estrogen Receptor-Positive BreastCancer: Traditional Prognostics, Molecular Pathology: A New Breast Cancer Taxonomy and 21st Century Personalized Prognostic and Predictive Assays.- Molecular Signatures in Melanoma Progression.- Promising New Treatments for Solid Tumors.- Targeted Therapy for Breast Cancer: A Focus on HER2/neu and Antiangiogenic Therapy.- Advances in the Treatment of Colorectal Cancer: Targeting Receptors of Disease.- Developments in the Management of Genitourinary Malignancies: Prostate Cancer and Renal Cell Carcinoma.- Advances in the Treatment of Lung Cancer.- Recent Advances in the Treatment of Melanoma.- Pegylated Interferons in the Adjuvant Treatment of Melanoma.- Sorafenib, a Multikinase Inhibitor: Results from Clinical Trials in Melanoma Patients.- Targeting Immunological Synapse: New Horizons in Immunotherapy for Cancer.- Cutaneous Metastases of Melanoma: New Treatment Options.- Neoadjuvant Approaches in Melanoma.- Implications of Chemo/Biochemotherapy in the Treatment of Metastatic Melanoma.- Future Perspectives.- Future Perspectives for Cancer Metastasis: Unanswered Questions and Unquestioned Answers.