Coordinating Organismal Physiology Through the Unfolded Protein Response

Häftad, Engelska, 2018

Del 414 i serien Current Topics in Microbiology and Immunology

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Beskrivning

This volume reviews the current research focused on the functional importance of unfolded protein response (UPR) signaling in the context of health and disease. The chapters present cutting-edge work describing the diverse functions of UPR signaling critical for regulating cellular and organismal physiology under physiologic and pathologic conditions. Written by internationally respected scientists, this volume is designed to provide a broad view of the diverse functional importance of UPR, and as such appeals to clinicians and academic researchers alike.

Produktinformation

Utgivningsdatum:2018-12-14
Mått:155 x 235 x 13 mm
Vikt:347 g
Format:Häftad
Språk:Engelska
Serie:Current Topics in Microbiology and Immunology
Antal sidor:213
Förlag:Springer Nature Switzerland AG
ISBN:9783030087234

Utforska kategorier

Fysiologi inom Medicin
Onkologi inom Medicin
Biovetenskap inom Naturvetenskap och teknik

Mer om författaren

R. Luke Wiseman Associate ProfessorDepartment of Molecular MedicineThe Scripps Research Institute MEM 220La Jolla, CA 92037, USAPhone: (858) 784-8820Email: wiseman@scripps.eduCole M. HaynesAssociate ProfessorUniversity of Massachusetts Medical SchoolWorcester, MA 01605, USAEmail:Cole.Haynes@umassmed.edu

Innehållsförteckning

Adapting Secretory Proteostasis and Function Through the Unfolded Protein Response.- Cell Non-Autonomous UPRER Signaling.- The unfolded protein response in the immune cell development: Putting the caretaker in the driving seat.- Mitochondria associated membranes and ER stress.- Coordinating Organismal Metabolism during Protein Misfolding in the ER Through the Unfolded Protein Response.- ER stress and neurodegenerative disease: a cause or effect relationship?- Driving cancer tumorigenesis and metastasis through UPR signaling.- ER Protein Quality Control and the Unfolded Protein Response in the Heart.