Optical Clearing Method

Luís Oliveira graduated in Physics in 2000 from Porto University – School of Sciences. Later, in 2010 and 2014, he received the M.S. and PhD degrees from the same University – School of Engineering. Since 2001 he has been a researcher in the field of optics, later specializing in the field of biophotonics. He is a Professor (Adjunct) at the Physics Department of the Polytechnic Institute of Porto – School of Engineering since 2008. He is also a senior researcher in biophotonics at the Center of Innovation in Engineering and Industrial Technology, a research center that is part of the Polytechnic of Porto. In recent years, Prof. Oliveira has reviewed and authored several papers in the fields of tissue optics and tissue optical clearing. He has one patent pending regarding the discovery of two tissue windows in the ultraviolet. His main research interests include tissue optics, tissue optical clearing and related clinical applications to diagnose and treat pathologies. Valery V. Tuchin is a professor and chair of Optics and Biophotonics at Saratov State University (National Research University of Russia) and several other universities and academic Institutes in Russia and abroad. His research interests include tissue optics, laser medicine, tissue optical clearing, and nanobiophotonics. He is a fellow of SPIE and OSA, he was awarded the Honored Science Worker of Russia, Honored Professor of Saratov State University, SPIE Educator Award, FiDiPro (Finland), Chime Bell Prize of Hubei Province (China), Joseph W. Goodman Book Writing Award (OSA/SPIE), and OSA Michael S. Feld Biophotonics Award for pioneering research in biophotonics. He has published more than 700 papers (Web of Science), 27 monographs and text-books, and 58 book chapters. Dr. Tuchin is also a holder of more than 50 patents. His works were cited 24,636 times to August, 2019 (Google Scholar).

• Chapter1. Tissue Optics.- Chapter2. Controlling the optical properties of biological materials.- Chapter3. Typical optical clearing agents.- Chapter4. Major optical clearing mechanisms.- Chapter5. Measurements during optical clearing.- Chapter6. Data that can be acquired from optical clearing studies.- Chapter7. Optical clearing and tissue imaging.- Chapter8. Other applications of OCAs.- Chapter9. Future perspectives of the optical clearing method.