Nuclear Receptors

Dr. Mostafa Z. Badr is a Professor Emeritus at the University of Missouri-Kansas City, USA. Dr. Badr obtained his Bachelor degree in Pharmacy and a Master’s degree in Organic Chemistry from the Faculty of Pharmacy, Cairo University, Egypt. Dr. Badr subsequently obtained a Ph.D. Degree in Pharmacology and Toxicology from the University of Louisville, after which he received postdoctoral training in Toxicology at the University of North Carolina-Chapel Hill. In 1987 Dr. Badr accepted the position of Assistant Professor at the University of Missouri-Kansas City School of Pharmacy, where he retired as Professor in 2015. Dr. Badr has authored and co-authored over 70 publications in peer-reviewed journals, and has published three previous books with Springer Nature. Dr. Badr founded the journal of PPAR Research and served as its Editor-in-Chief from 2005-2011, and the journal of Nuclear Receptor Research and served as its Editor-in-Chief from 2013 until 2019. Mostafa Badr, Ph.D.Kansas City, MO, USANovember 2020.

• 1. Molecular Pharmacology of the Youngest Member of the Nuclear Receptor Family: The Mineralocorticoid Receptor.- 2. A Simple Method for Visual Assessment and Quantification of Altered Subcellular Localization of Nuclear Receptors.- 3. Multifaceted Effects of Ligand on Nuclear Receptor Mobility.- 4. Chemical Considerations in Discovery of Receptor Modulators.- 5. Structure-Based Design of Estrogen-Related Receptors Modulators.- 6. PPARα and δ ligand design – Honing the traditional empirical method with a more holistic overview.- 7. Pregnane X Receptor: understanding its function and activity at the molecular level.- 8. Ligand Design for the Vitamin D Receptor.- 9. What Makes a Good Antagonist: Lessons Learned from the Estrogen and Aryl Hydrocarbon Receptors.- 10. Design of Novel PPAR agonist for Neurodegenerative Disease.- 11. Functional bioassays lithograph ligand reflections in the PPARalpha sphere.- 12. Computational applications on Food Contact Chemicals as Nuclear Receptors binders.- 13. Alternation of Nuclear Hormone Receptor Signaling by Antiviral Drugs.- 14. Retinoic acid-related orphan receptor (ROR) inverse agonists: potential therapeutic strategies for multiple inflammatory diseases.- 15. Therapeutic Strategies to Target Activating Estrogen Receptor a Mutation.- 16. Androgen Receptors in the Pathology of Disease.- 17. Bilirubin: A Ligand of the PPARα Nuclear Receptor.- 18. Nuclear Receptor Ligands in Flavivirus Infection Control.- 19. Use of Nanotechnology to Improve 15d-PGJ2 Immunomodulatory Activities.- 20.Ligand-independent Activation of PPARs.- 21. PPAR Modulation Through Posttranslational Modification Control.- 22. Developing Inhibitors to the Amino-Terminus Domains of Steroid Hormone Receptors.- 23. Redirecting the cellular waste disposal machinery to target transcription.