This book constitutes the proceedings of the 17th International Symposium on Applied Reconfigurable Computing, ARC 2021, held as a virtual event, in June 2021.The 14 full papers and 11 short presentations presented in this volume were carefully reviewed and selected from 40 submissions. The papers cover a broad spectrum of applications of reconfigurable computing, from driving assistance, data and graph processing acceleration, computer security to the societal relevant topic of supporting early diagnosis of Covid infectious conditions.