The two-volume set ICAISC 2024 15164, 15165 and 15166 constitutes the refereed proceedings of the 23rd International Conference on Artificial Intelligence and Soft Computing, ICAISC 2024, held in Zakopane, Poland, during June 16–20, 2024.The 96 full papers included in this book were carefully reviewed and selected from 179 submissions. They are organized in topical sections as follows:Part I - neural networks and their applications; pattern classification.Part II - evolutionary algorithms and their applications; artificial intelligence in modeling and simulation; computer vision, image and speech analysis.Part III - various problems of artificial intelligence; bioinformatics, biometrics and medical applications.