This book offers a current overview of Tissue Engineering and Regenerative Medicine (TERM), highlighting key technological and methodological advances. It introduces core TERM concepts and strategies for tissue and organ regeneration, along with the bioengineering of tissue models based on modern principles. Chapters cover scaffold design and fabrication—especially additive manufacturing—cell-biomaterial interactions, and computational modeling of scaffold behavior. Clinical applications are included to illustrate real-world relevance. The book also explores cutting-edge topics such as bioprinting, microfluidic devices, and organoids in the development of biomimetic tissue models. Each chapter ends with a “Questions” section to help readers review and reinforce key concepts.