This open access book constitutes the refereed proceedings of the 13th Annual Privacy Forum on Privacy Technologies and Policy, APF 2025, held in Frankfurt am Main, Germany, during October 22-23, 2025.The 9 full papers were carefully reviewed and selected from 27 submissions.They were organized into following topical sections: Supporting Laypeople and Users: Design Approaches, User Perceptions, and Problems; Emerging Risks from Upcoming Technologies, Misunderstandings, and Regulatory Derogation; Professional Methods & Tools for Analysis and Decision Making.