Global Trends in Health, Technology and Management II

Anil Kumar Saxena, Chairman of the Global Institute of Pharmaceutical Education and Research, is a leading authority in Medicinal Chemistry and Computer-Aided Drug Design (CADD). Former Chief Scientist at CDRI, Lucknow, he has 50+ years of research experience, 230 publications, 72 patents, and has mentored 45 Ph.D. scholars. A pioneer of QSAR and CADD in India, Dr. Saxena is ranked among the top 2% scientists worldwide by Stanford University for five consecutive years. He is a Fellow of the Royal Society of Chemistry (UK), recipient of the Alexander von Humboldt Fellowship, and serves as Series Editor for Topics in Medicinal Chemistry (Springer). His editorial work includes Communicable diseases of the developing World- Vol. 29, Biophysical Tools in Computational Drug Discovery – Vol. 37 and GTHTM-2024 Proceedings.Aaruni Saxena, MD, PhD, MRCP, MBA, is a clinician-researcher specializing in internal medicine, oncology, and clinical pharmacology. A Fellow of the United Nations and the International Society for Infectious Diseases, he has worked with the World Health Organization on global health strategies and clinical trial protocols.Currently a Specialty Registrar in Oncology at Nottingham University Hospitals, Dr. Saxena holds dual medical certifications from Germany, a Ph.D. in Clinical Pharmacology, and an MBA in International Organizations from the University of Geneva. His research includes drug interactions, cardiovascular pharmacology, and molecular modeling, with multiple peer-reviewed publications.

• Innovations in Drug Design: Case Studies from Discovery to Development.- Development of Allosteric Inhibitors against Cyclin-Dependent Kinase 2 (CDK2).- Evaluation of 2-phenylthiazolidin-4-one analogues as inhibitors of the SARS-CoV-2 main protease.- Engineered Antibiotics: A Strategy to Combat Multi-Drug-Resistant Bacteria: A Review on Antibiotics Modification.- In silico studies of 1,2,4-triazole derivatives by targeting DHFR againsts staphylococcus aureus: Pharmacophore generation, Atom-based 3D-QSAR, Molecular docking and ADMET.- Rationale of Antifungal And Anti Bacterial Interventions Of Imidazole Derivatives.- Quantitative Structure Pharmacophore–Activity Relationship of Tricyclic Antidepressant (TCAs) Utilizing Distance–Based Features.- Computational Design of Pyrazole Derivatives for Management of Autoimmune Disease.- Designing, Synthesis and Characterization of Novel Heterocyclic Derivatives of-oxothiazolidine-3-carbonyl)-6- substituted-spiro[indoline-2,2'-thiazolidine]-3,4'-dione and -oxothiazolidine-3-carbonothioyl)-6- substituted-spiro [indoline-2,2'-thiazolidine]-3,4'-dione and their Bioevaluation.- Synthesis and Antimicrobial Evaluation of Novel dioxo spiro[indoline-3,2' thiazolidin]-3'-yl)thiourea and -dioxaspiro[indoline-3,2'-thiazolidin]-3'-yl)urea.