This book constitutes the refereed proceedings of the First EAI International Conference on Responsible Artificial Intelligence and Data Science, RAIDS 2024, held in Danang, Vietnam, during October 22–24, 2024.The 16 full papers presented in this volume were carefully reviewed and selected from 39 submissions. They were organized in the following topical sections: AI for Healthcare and Medical Applications; AI for Human Services and Social Applications; Theorical Contributions for Responsible AI.