This book sheds new light on the complex phenomenon of cell fusion, a vital process in various physiological and pathophysiological contexts, including fertilization, placentation, myogenesis, and cancer. While the merging of cells may seem straightforward, it involves a sophisticated interplay of biological mechanisms that are not yet fully understood. In this new edition, readers will discover insights into the interplay of lipids and peptides in membrane fusion, the role of cell fusion in fertilization and placentation, and the implications of fusion deficiencies in pregnancy diseases. The book also examines the transformation of non-fusogenic cells, such as macrophages and cancer cells, under extrinsic conditions, and the potential link between cell fusion and cancer malignancy through genetic/epigenetic instability. Contributions from leading experts provide a thorough analysis of these topics, inviting readers to explore critical questions about the role of cell fusion in physiology and pathophysiology.This volume is an essential resource for researchers, scholars, and students in the fields of cell biology, oncology, and virology, offering valuable insights into the mechanisms and implications of cell fusion.
