String Processing and Information Retrieval

This book constitutes the refereed proceedings of the 33rd International Symposium on String Processing and Information Retrieval, SPIRE 2026, held in Hamilton, ON, Canada, during October 2026.The 19 full papers and 4 short papers included in this book were carefully reviewed and selected from 47 submissions. SPIRE continues the long and well-established tradition of encouraging high-quality research at the broad nexus of string processing, information retrieval, and computational biology.