B Cell Receptor Signaling

Inbunden, Engelska, 2016

Del 393 i serien Current Topics in Microbiology and Immunology

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Beskrivning

Altogether, the discoveriespresented provide a better understanding of B cell biology and help to explainsome B cell-mediated pathogenicities, like autoimmune phenomena or theformation of B cell tumors, whilealso paving the way for eventually combating thesediseases.

Produktinformation

Utgivningsdatum:2016-01-06
Mått:155 x 235 x 19 mm
Vikt:530 g
Format:Inbunden
Språk:Engelska
Serie:Current Topics in Microbiology and Immunology
Antal sidor:231
Upplaga:16001
Förlag:Springer International Publishing AG
ISBN:9783319261317

Utforska kategorier

Onkologi inom Medicin
Medicinsk utrustning och medicinska tekniker inom Medicin

Mer om författaren

Tomohiro Kurosaki, MD, PhD, is a professor at WPI Immunology Frontier Research Center at Osaka University, JapanJürgen Wienands, PhD, is a professor of Cellular and Molecular Immunology at the University of Göttingen, Germany

Innehållsförteckning

Assembly and function of the precursor B-cell receptor.- Receptor Dissociation and B cell activation.- Molecular mechanisms of B cell antigen gathering and endocytosis.- BTK signaling in B cell differentiation and autoimmunity.- The memory function of the B cell antigen receptor.- PI3K signaling in normal B cells and chronic lymphocytic leukemia (CLL).- Role of Calcium Signaling in B Cell Activation and Biolog.- Roles of the NF-kappaB pathway in B-lymphocyte biology.- MAP kinase cascades in antigen receptor signaling and physiology.