The 16thInternational Symposium on MEMS and Nanotechnology, Volume 5 of the Proceedings of the 2015SEM Annual Conference& Exposition on Experimental and Applied Mechanics, the fifth volume of nine from the Conference, brings together contributions to this important area of research and engineering.  The collection presents early findings and case studies on a wide range of areas, including: Microscale and Microstructural Effects on Mechanical BehaviorDynamic Micro/NanomechanicsIn-situ TechniquesMechanics of GrapheneIndentation and Small Scale TestingMEMS