Adam S. Cheifetz, MDBeth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USAJoseph D. Feuerstein, MDBeth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA

• Mechanism of Action and Pharmacokinetics of Biologics.- Anti-tumor Necrosis Factor Agents in Ulcerative Colitis.- Anti-tumor Necrosis Factor Agents in Crohn’s Disease.- Anti-TNF Therapy for Treatment of Extraintestinal Manifestations of Inflammatory Bowel Disease.- Use of Biologics in the Postoperative Management of Crohn’s Disease.- Biologics in Pregnancy and Breastfeeding.- Concomitant Use of Immunosuppressive Therapy with Tumor Necrosis Factor (TNF) Antagonists in Inflammatory Bowel Disease.- Therapeutic Drug Monitoring of Biologic Agents.- Use of Biologics in Crohn’s Disease and Ulcerative Colitis Prior to Surgery and Perioperative Risks.- Cessation of Biologics – Can it be Done?.- Biologic Therapy in Pediatric Inflammatory Bowel Disease.- Infectious Complications of Biologics.- Tumor Necrosis Factor-Alpha Inhibitors and Risks of Malignancy.- Non-infectious and Non-malignant Complications of Biologics.- Biosimilars in Inflammatory Bowel Disease 2017: State of the Science, State of the Art, State of the Finances.- Anti-Integrin Agents in IBD: Efficacy and Risk of Complications.- Novel Agents in Inflammatory Bowel Disease.- Quality, Safety, and Practical Considerations of Using Biologic Therapies.