Point-of-Care Tests for Severe Hemorrhage

“Reading this manual for the diagnosis and treatment of coagulopathy is highly recommended for both beginners learning to use point-of-care testing (POCT) for coagulation monitoring and experienced users. It is comprised of thorough basic information including how to do the tests, how they work, and how to interpret test results as well as the descriptions of new developments and prototype devices that serve as food for thought regarding strategic evolvement and future clinical trials.” (Sibylle Kozek-Langenecker, Anesthesia & Analgesia, Vol. 124 (1), January, 2017)“This is a collection of reviews that describe bedside testing modalities enabling dissection of the etiology of hemorrhage in a variety of clinical settings. … Any clinician managing the bleeding patient, including intensivists, traumatologists, anesthesiologists, obstetricians, and hematologists, may benefit from this book. … This is an excellent summary of the physiological basis and potential application of a collection of technologies that are receiving significant attention in the management of the bleeding patient.” (David J. Dries, Doody's Book Reviews, March, 2016)“The first edition of this manual successfully achieved the objectives of the authors in compiling current, comprehensive, and relevant information on POCTs and their application in various severe hemorrhage scenarios. This textbook will appeal to a broad readership of trainees and clinicians of different disciplines involved in the management of this challenging group of patients.” (Carlos Corredor, Canadian Journal of Anesthesia, Vol. 63, 2016)

• Pathophysiology of coagulation.- General aspects of viscoelastic tests.- General aspects of platelet function tests.- Other POC tests.- POC tests in clinical practice: history.- Blood derivates and prohemostatic drugs.- Clinical management of severe bleeding in trauma patients.- Clinical management of severe bleeding in cardiovascular patients.- Clinical management of post-partum hemorrhage.- Clinical management of severe bleeding in liver surgery.- Disorders of hemostasis in critically ill patients.- Assessment of the effects of antithrombotic drugs.- Practical issues in POC tests.- Clinical cases.