Chronic Myeloid Leukemia

Rüdiger Hehlmann is a Professor of Medicine at the Mannheim Medical Faculty of the University of Heidelberg, Germany. Professor Hehlmann is past Chief of Medicine at Mannheim, past President of the German Society of Hematology and Oncology, past Dean of his faculty, and past Secretary General of the International Association of Comparative Research on Leukemia and Related Diseases (IACRLRD). He is founder and chair of the German CML Study Group, of the German Competence Network on acute and chronic leukemias, and of the European LeukemiaNet. He is an honorary member of the Polish and German Societies for Hematology and honorary doctor of the University of Uppsala, Sweden. He has received various awards for leukemia research and interdisciplinary cooperation. His research interests focus on leukemia, in particular CML, on mechanisms of leukemogenesis, and on progression to blast crisis.

• Cytogenetics of CML.- The biology and pathogenesis of CML.- The choice of 1st line CML‐treatment.- A review and up‐date of the European LeukemiaNet recommendations for the management of CML.- Management of adverse events associated with ATP‐competitive BCR‐ABL 1 tyrosine kinase inhibitors in CML.- Standardization of molecular monitoring for CML.- Epidemiology of CML.- Prognostic scores for patients with CML under particular consideration of disease specific death.- Response‐related predictors of survival.- CML‐ blast crisis: implications and management.- Chronic Myeloid Leukemia and Pregnancy.- The role of hematopoietic stem cell transplantation in CML.- Discontinuation or cessation of tyrosine kinase inhibitor treatment in CML patients with deep molecular response.- The interferon‐alpha revival in CML.- Changing the cost of care for CML: the availability of generic imatinib.