Isolation and Molecular Characterization of Circulating Tumor Cells

Häftad, Engelska, 2018

Del 994 i serien Advances in Experimental Medicine and Biology

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Beskrivning

Numerous studies have shown that elevated levels of circulating tumor cells (CTCs) in blood of cancer patients are associated with poor response to treatment and inferior survival probabilities.

Produktinformation

Utgivningsdatum:2018-08-02
Mått:155 x 235 x 18 mm
Vikt:487 g
Format:Häftad
Språk:Engelska
Serie:Advances in Experimental Medicine and Biology
Antal sidor:301
Förlag:Springer International Publishing AG
ISBN:9783319857879

Utforska kategorier

Onkologi inom Medicin

Innehållsförteckning

Preface.- Circulating Tumor Cells as Cancer Biomarkers.- Strategies for Isolation and Molecular Profiling of Circulating Tumor Cells.- Aptamer-Based Methods for Detection of Circulating Tumor Cells and Their Potential for Personalized Diagnostics.- Development of a Protocol for Single-Cell Analysis of Circulating Tumor Cells in Patients with Solid Tumors.- Flow Cytometric Methods for Circulating Tumor Cell Isolation and Molecular Analysis.- Enrichment and Detection of Circulating Tumor Cells and Other Rare Cell Populations by Microfluidic Filtration.- Detection and Enumeration of Circulating Tumor Cells with Invasive Phenotype.- Molecular Profiling and Significance of Circulating Tumor Cell Based Genetic Signatures.- Detection of Gene-Rearrangements in Circulating Tumor Cells: Examples of ALK-, ROS1-, RET-Rearrangements in Non-Small-Cell Lung Cancer and ERG-Rearrangements in Prostate Cancer.- Enrichment, Isolation, and Molecular Characterization of EpCAM-Negative Circulating Tumor Cells.- Expression of Epithelial Mesenchymal Transition and Cancer Stem Cell Markers in Circulating Tumor Cells.