Infections Causing Human Cancer

Softcover Edition

Häftad, Engelska, 2010

880 kr

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Beskrivning

Infections must be thought as one of the most important, if not the most important, risk factors for cancer development in humans. Approximately 15-20% of all cases of cancer around the world are caused by viruses. Theestablishment of a causal relationship between the presence of specific infective agents and certain types of human cancer represents a key step in the development of novel therapeutic and preventive strategies. In this book, Professor zur Hausen (Nobel Prize in Physiology/Medicine 2008) provides a thorough and comprehensive overview on carcinogenic infective agents -- viruses, bacteria, parasites and protozoons -- as well as their corresponding transforming capacities and mechanisms. The result is an invaluable and instructive reference for all oncologists, microbiologists and molecular biologists working in the area of infections and cancer. The author was among the first scientists to reveal the cervical cancer-inducing mechanisms of human papilloma viruses and isolated HPV16 and HPV18, and, as early as 1976, published the hypothesis that wart virusesplay a role in the development of this type of cancer.

Produktinformation

Utgivningsdatum:2010-10-27
Mått:173 x 241 x 25 mm
Vikt:1 007 g
Format:Häftad
Språk:Engelska
Antal sidor:531
Förlag:Wiley-VCH Verlag GmbH
ISBN:9783527329779

Utforska kategorier

Onkologi inom Medicin

Mer om författaren

From 1983 until his retirement in 2003, Harald zur Hausen acted as chairman of the management board and scientific director of the German Cancer Research Center in Heidelberg until his retirement in. Previously he worked at a number of different universities in the USA and Germany. Professor zur Hausen has served on a large number of different scientific and policy bodies in many different countries including the European Board of Directors of HUGO, the International Scientific Advisory Committee of the French National Cancer Institute and Vice-Chairman of the German American Academic Council. In 2008 Professor zur Hausen was awarded the Nobel Prize in Physiology/Medicine for his research on the relationship between infections and cancer. Among his many other awards, he has held the Robert Koch Award, the Charles S. Mott Prize of the General Motors Cancer Research Foundation, the Paul Ehrlich and Ludwig Darmstaedter Award, the German Cancer Award, and the Federal Order of Merit, as well as six honorary degrees and seven visiting professorships.

Recensioner i media

"You should consider purchasing it." Lab Times

Innehållsförteckning

HISTORICAL REVIEWThe Early Period (1898-1911)Frustration and Successes (1912-1950)The Period from 1950 to 1965A First Human Tumor Virus?The Difficult 1970sThe Re-emergence of a ConceptTHE QUEST FOR CAUSALITYInfectious Agents as Direct CarcinogensInfectious Agents as Indirect CarcinogensTUMORS LINKED TO INFECTIONS -SOME GENERAL ASPECTSTumor Types Linked to InfectionsGlobal Contributions of Infections to Human CancerHost Interactions with Potentially Carcinogenic InfectionsHERPESVIRUSES AND ONCOGENESISAlphaherpesviridaeBetaherpesviridaeGammaherpesviridaePAPILLOMAVIRUSES -A MAJOR CAUSE OF HUMAN CANCERSIntroductionConcept of Viral Interfering CascadesCancers Linked to HPV InfectionsRole of Co-factorsPreventive VaccinationTherapeutic VaccinationTherapyHEPADNAVIRUS FAMILYHepatitis B VirusAnimal HepadnavirusesFLAVIVIRUS FAMILYHepatitis C VirusRETROVIRUS FAMILYHuman T-lymphotropic Retroviruses 1 (HTLV-1)Human T-lymphotropic Retroviruses 2 (HTLV-2)Human Endogenous RetrovirusesGibbon Ape Leukaemia Virus and Simian Sarcoma VirusOTHER VIRUS INFECTIONS POSSIBLY INVOLVED IN HUMAN CANCERSPolyomaviruses (JC, BK and SV40)HELICOBACTER, CHRONIC INFLAMMATION AND CANCERDiscovery, Taxonomy and GenomicsLife Cycle, Specificity, and Virulence Determinants in Cancer DevelopmentPrevention of H. Pylori Induced CancerAnimal ModelsVirulence Determinants of Enterohepatic Helicobacter SppEnterohepatic Helicobacter Spp. -Are they Cocarcinogens?PARASITES AND HUMAN CANCERSchistosomiasisInfection with Liver Flukes (Opisthorchis Viverrini, O. Felineus, Clonorchis Sinensis)CANCERS WITH A POSSIBLE INFECTIOUS ETIOLOGYLeukemias and LymphomasHuman Breast CancerOther Human Cancers Possibly Linked to Infectious Events