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      1. Naturvetenskap och teknik
      2. Matematik och naturvetenskap
      3. Kemi

      Validation in Chemical Measurement

      AvPaul De Bièvre,Helmut Günzler

      Inbunden, Engelska, 2004

      1 113 kr

      Beställningsvara. Skickas inom 10-15 vardagar. Fri frakt över 249 kr.

      Beskrivning

      Validationofmeasurementmethodshasbeenusedforavery ciated measurement uncertainty? The answer must be: no. longtimeinchemistry. Itismostlybasedontheexamination Therecanneverbeamechanismorrecipeforproducing - of a measurement procedure for its characteristics such as tomatically 'valid' results because one can never eliminate precision, accuracy, selectivity, sensitivity, repeatability, re- theskills,theroleandtheresponsibilityoftheanalyst. producibility,detectionlimit,quanti?cationlimitandmore. ISO 9000:2000, item 3. 8. 5 de?nes validation as 'con?r- When focussing on quality comparability and reliability mation by examination and provision of objective evidence in chemical measurement, the ?elds of interest to this Jour- that the requirements for an intended use are ful?lled'. The nal, one stumbles into various interpretations of the term revised edition of the VIM ('VIM3'), is likely to ?ne-tune validation. It is one more example of a term which is used thisde?nitionoftheconcept'validation'tobe'con?rmation sometimes very consistently, sometimes very loosely or in- through examination of a given item and provision of - deed ambiguously.Since the term is very common in the jective evidence that it ful?lls the requirements for a stated chemical community, it is important that its meaning be intendeduse'. nd clear. Turning to the 2 edition of the International Vo- Lookingatsimplepractice, manypeoplearelookingfor cabulary of Basic and General terms in Metrology (VIM) aformaldecisionthatagivenmeasurementmethod automat- (1993), surprisingly we do not ?nd a de?nition. Webster's ically gives them 'valid' i. e. reliable results. One wonders Dictionary of the English language (1992) tells us that val- what this has to do with 'stated intended use'. Reliab- idation is 'making or being made valid'. Obviously valida- ity clearly is a property of a measurement result.

      Produktinformation

      • Utgivningsdatum:2004-12-08
      • Mått:210 x 277 x 15 mm
      • Vikt:708 g
      • Format:Inbunden
      • Språk:Engelska
      • Antal sidor:168
      • Upplaga:2005
      • Förlag:Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
      • ISBN:9783540207887

      Utforska kategorier

      • Kemi inom Naturvetenskap och teknik
      • Naturvetenskap:allmänt inom Naturvetenskap och teknik

      Recensioner i media

      From the reviews: "The world at large has become more aware of the importance of analytical measurements and their role in defining what quality is acceptable and what is not! ... overall this is a useful compilation and would serve as a good introduction to and an overview of the field for practicing analytical chemists and scientists particularly from certified laboratories (ISO 17025 etc)." (C. Burgess, Chromatographia, Vol. 62 (3-4), 2005) "Validation is certainly a hot topic in analytical chemistry since a couple of decades. It is not only an important topic in education of chemical students, but first of all the subject of interest for routine laboratories. ... There is no doubt, that in the field where many analytical chemist consider themselves as experts, such book brings much new and useful information ... . I am sure that this book will be appreciated by many newly educated as well as experienced analysts." (Adam Hulanicki, Chemia Analityczna, Vol. 50, 2005)

      Innehållsförteckning

      • Bioanalytical method validation and its implications for forensic and clinical toxicology — A review.- Validation of a computer program for atomic absorption analysis.- Instrumental validation in capillary electrophoresis and checkpoints for method validation.- Qualification and validation of software and computer systems in laboratories.- Clinical reference materials for the validation of the performance of photometric systems used for clinical analyses.- Measurement uncertainty and its implications for collaborative study method validation and method performance parameters.- Qualification and validation of software and computer systems in laboratories.- Qualification and validation of software and computer systems in laboratories.- Qualification and validation of software and computer systems in laboratories.- Analytical validation in practice at a quality control laboratory in the Japanese pharmaceutical industry.- Validation of the uncertainty evaluation for the determination of metals in solid samples by atomic spectrometry.- Validation requirements for chemical methods in quantitative analysis — horses for courses?.- Validation criteria for developing ion-selective membrane electrodes for analysis of pharmaceuticals.- Is the estimation of measurement uncertainty a viable alternative to validation?.- Validation of an HPLC method for the determination of p-dichlorobenzene and naphthalene in mothrepellents.- The evaluation of measurement uncertainty from method validation studies.- The evaluation of measurement uncertainty from method validation studies.- Automated ion-selective measurement of lithium in serum. A practical approach to result-level verification in a two-way method validation.- Determination of hydrocarbons in water — interlaboratory methodvalidation before routine monitoring.- Interlaboratory quality audit program for potable water — assessment of method validation done on inductively coupled plasma atomic emission spectrometer (ICP-AES).- A need for clearer terminology and guidance in the role of reference materials in method development and validation.- Validation of salt spray corrosion test.- Method validation and reference materials.- Method validation of modern analytical techniques.- Validation of test methods.- Marketing Valid Analytical Measurement.- Analytical procedure in terms of measurement (quality) assurance.- Flexibilization of the scope of accreditation: an important asset for food and water microbiology laboratories.- Different approaches to legal requirements on validation of test methods for official control of foodstuffs and of veterinary drug residues and element contaminants in the EC.- Methods validation: AOAC’s three validation systems.- Observing validation, uncertainty determination and traceability in developing Nordtest test methods.
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