Microanatomy and Function of the Spleen

Häftad, Engelska, 1999

Del i serien Advances in Anatomy, Embryology and Cell Biology

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Beskrivning

This title is intended for scientists and lecturers working in the fields where anatomy and immunology meet. A basic knowledge of microscopical anatomy and somewhat more advanced knowledge of immunology is a prerequisite. This is the only recent publication correlating splenic microanatomy and function in man and rodents. The immunohistological findings are documented by colour plates.

Produktinformation

Utgivningsdatum:1999-09-20
Mått:155 x 235 x 7 mm
Vikt:184 g
Format:Häftad
Språk:Engelska
Serie:Advances in Anatomy, Embryology and Cell Biology
Antal sidor:96
Förlag:Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
ISBN:9783540661610

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Innehållsförteckning

1 Introduction.- 2 Materials and Methods.- 2.1 Animal Spleens.- 2.2 Human Spleens.- 2.3 Antibodies.- 2.4 Single Staining Procedure for Immunohistology.- 2.5 Double Staining Procedure for Immunohistology.- 2.6 Demonstration of Acid Phosphatase in Cryostat Sections.- 2.7 Demonstration of Alkaline Phosphatase in Cryostat Sections.- 3 Microanatomical Compartments of the Rat Spleen.- 3.1 White Pulp.- 3.2 Red Pulp and Splenic Vessels.- 3.3 Summary.- 4 Microanatomical Compartments of the Human Spleen.- 4.1 White Pulp.- 4.2 Red Pulp and Splenic Vessels.- 4.3 Summary.- 5 Function of Splenic Compartments.- 5.1 Splenic White Pulp Compartments during Primary T Cell-Dependent Antibody Responses against Protein Antigens.- 5.2 Function of the Marginal Zone during Primary Antibody Responses against T Cell-Independent Type 2 Antigens.- 5.3 Function of the Red Pulp.- 5.4 Role of the Spleen in CD8+ Cytotoxic T Cell Responses.- 5.5 The Spleen, Natural Killer Cells and Gamma/Delta T Cells.- 6 Recirculation of Lymphocytes Through the Spleen.- 6.1 Summary.- 7 The Role of Cytokines and Chemokines in the Development of Splenic Compartments.- 7.1 Summary.- 8 Unsolved Problems of Human Splenic Structure and Function.- 8.1 Arterial Blood Supply to the Splenic Follicles and to the Perifollicular Zone.- 8.2 Blood Circulation in the Splenic Red Pulp: Subpopulations of Fibroblasts and their Role.- 8.3 Function of Sheathed Capillaries.- 8.4 Lymphocyte Migration in the Human Splenic White Pulp — A Hypothesis.- 9 Summary.- References.