The chapters are written by well recognized experts in their field of intensive care and emergency medicine. It is addressed to everyone involved in internal medicine, anesthesia, surgery, pediatrics, intensive care and emergency medicine.
Sepsis and Inflammation.- The Molecular Genetics of Sepsis: Clinical Epidemiology Considerations.- The Role of Interleukin (IL)-12 and IL-18 During Endotoxemia and Bacterial Infection.- The Apoptotic Response of the Lymphoid Immune System to Trauma, Shock, and Sepsis.- Modulation of Neutrophil Function in Sepsis.- Trauma-Induced Immunosuppression: Pathogenesis and Treatment.- The Influence of Nutrition on Mucosal Immunology and Endothelial Cell Adhesion Molecules.- Intestinal Microcirculation: Changes in Sepsis and Effect of Vasoactive Manipulation.- Microvascular Permeability in Experimental Sepsis: Mechanisms, Modulation and Management.- Infectious Challenges.- Catheter-Related Infections in the ICU.- Ecological Impact of Beta-lactam Treatment on Normal Human Intestinal Microflora.- Non-Pharmacologic Prevention of Ventilator-Associated Pneumonia (VAP).- Fungal Infections.- Fungal Infections in Critically Ill Surgical Patients.- Candida: Some Thoughts.- Steroid Therapy.- Clinical Impact of Glucocorticoid Pharmacodynamics.- Corticosteroids in the Acute Respiratory Distress Syndrome.- Corticosteroid Therapy in Critical Illness: A Changing Paradigm.- Pathophysiology of Lung Injury.- Alveolar Epithelial Barrier: Acute Lung Injury.- Pulmonary Oxygen Toxicity in Man: Emerging Concepts in Pathogenesis and Prevention.- Fibrosis in ARDS: How Close is the Link between Inflammation and Fibroproliferation?.- The Clinical Relevance of Exhaled Nitric Oxide: A Critical Review.- Acute Respiratory Failure.- Hypoxemia and Mortality in the ICU.- Diffuse Alveolar Hemorrhage in the ICU.- Optimal Positioning for the Adult Intensive Care Patient while Prone.- Mechanical Ventilation.- Utilization of Mechanical Ventilation in Critical Care.- Respiratory Physiology as a Basis for the Managementof Acute Lung Injury.- High Frequency Oscillatory Ventilation: A Tool to Decrease Ventilator-Induced Lung Injury?.- Extubation Failure.- Non-invasive Ventilation: Why Does It Fail?.- Surgery.- Reducing the Morbidity and Mortality of High-Risk Surgical Patients.- Causes of Oxygenation Impairment During Anesthesia.- Respiratory Function in Obese Patients in the Peri-operative Period.- Post-operative Myocardial Ischemia and Infarction.- Abdominal Crises.- Novel Strategies for the Management of Severe Acute Pancreatitis.- The Hepatorenal Syndrome.- Sedation.- Sedation in the Intensive Care Environment.- Intensive Care Sedation: The Alpha-2 Agonists.- Intravenous Fluids.- Fluid Therapy: Present Controversies.- Crystalloids versus Colloids in the Treatment of Hypovolemic Shock.- Human Albumin on the ICU: Can We Live Without It?.- Intra-operative Use of Hypertonic Solutions.- Adverse Effects of Colloids on Renal Function.- Should Old Red Cells be Transfused in Critically Ill Patients?.- Current Status of Artificial Oxygen Carriers.- Emergencies.- Intensive Care in a Forward Deployed Military Field Surgical Combat Support Hospital.- Diagnosis of Traumatic Aortic Injuries.- Diagnosis and Treatment of Hyperosmolar Emergencies.- Neurology.- Conservative and Invasive Treatment of Space-Occupying Hemispheric Stroke.- Thrombolytic Therapy for Intraventricular and Intraparenchymal Hemorrhage.- Cerebral Function in Vegetative State studied by Positron Emission Tomography.- Cardiovascular Crises.- Evaluation of Platelet Membrane Glycoproteins in Ischemic Heart Disease.- Coronary Thrombosis and Myocardial Infarction.- Diagnosis and Treatment of Tachycardias.- Cardiopulmonary Resuscitation: Lessons from the Past and Trends for the Future.- Effects of Catecholamine Therapy on Regional Perfusion in Septic Shock.- ICU Monitoring.- Evaluation of Cardiac Output and Cardiac Preload.- Transesophageal Echocardiography: The Relationship between Pressure, Flow and Function.- Respiratory Changes in Arterial Pressure in Mechanically Ventilated Patients.- The Study of the Microcirculation using Orthogonal Polarization Spectral Imaging.- Assessment of Tissue Oxygenation in the Critically Ill.- Blood Gas Monitoring with Optodes.- Interpretation of Changes in Regional and Mucosal PCO2, Gradients: The Haldane Effect.- The Meaning of Lactate.- Routine Assessment of Tissue Metabolism in the Critically Ill.- ICU Costs.- The Costs of Infection in the ICU.- Costs of Antibiotic Therapy: Maximizing Effectiveness While Minimizing Cost.- Clinical Pathways as a Tool for ‘Intelligent’ Rationing in Intensive Care.- 2000 and Beyond.- The Constraints and Necessity of Teaching Emergency Medicine to Medical Students.- ICU Organization: Does it Matter?.- Training of Young Intensivists in Management Skills for the New Millennium.- Outcome Prediction in Intensive Care.- Critical Care in the Elderly: The Final Challenge.
